Tổng Quan
- Danh pháp khoa học
- Plectranthus fruticosus L'Hérit.
- Họ thực vật
- Lamiaceae (Labiatae)
- Bộ phận dùng
- Leaves (research-only steam distillation; no commercial supply)
- Phương pháp chiết xuất
- Steam distillation (research-only; non-commercial)
- Màu sắc
- —
- Phân loại nốt hương
- Nốt Top/Middle
- Hương thơm
- —
- Chemotype / Cultivar
- —
Các quốc gia sản xuất chính
Tình trạng tại Việt Nam
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Herbaceous-piney, slightly camphoraceous, sage-like, terpene-fresh, cooling-sharp (theoretical — never-commercial)
Cây cỏ-thông, hơi long-não, giống xô thơm, terpene-tươi, mát-sắc (lý thuyết — chưa thương mại)
2–4 giờ
Tên gọi tại Việt Nam
Pha Chế & Hòa Hợp
Sabinyl acetate (>60%) disrupts uterine implantation via anti-nidation mechanisms demonstrated at 70 mg/kg sc in mice (Pages et al 1996); classified as a severe reproductive hazard, not a therapeutic endpoint.
Ref: Pages, N. et al (1996) Phytother. Res. 10:438-440; Pages, N. et al (1988) Planta Med. 54:296-298
Dose-dependent teratogenicity (microphthalmia, anophthalmia, hydrocephalus, cerebral hemorrhage) in rats oral 0.5–5.0 mg/kg GD6-15 and embryotoxicity in mice sc 15–135 mg/kg GD6-15; the strongest documented EO reproductive toxicity signal in B216 corpus.
Ref: Pages, N. et al (1988) Planta Med. 54:296-298; Pages, N. et al (1991) Phytother. Res. 5:94-96; Tisserand & Young 2014 Ch.11
Leaf decoctions (NOT the EO) used in Romanian traditional medicine; the therapeutic targets are unverified and the plant-vs-EO distinction is critical — concentrated EO is a documented reproductive toxicant at doses far below folk-herb preparation levels.
Ref: B216 Tisserand & Young 2014 Ch.13 p.778 — Romanian traditional medicine ethnobotanical context
AI-summary
No RCT-grade clinical evidence exists for Plectranthus fruticosus EO. All available evidence is preclinical reproductive toxicology. Pages et al (1988) demonstrated dose-dependent teratogenicity in rats (oral 0.5, 2.5, 5.0 mg/kg GD6-15 — microphthalmia, anophthalmia, hydrocephalus, cerebral hemorrhage with no maternal toxicity at any dose). Pages et al (1991) confirmed embryotoxicity in mice (sc 15, 45, 135 mg/kg GD6-15 — kidney and heart defects, skeletal alterations, anophthalmia). Pages et al (1996) isolated sabinyl acetate as the anti-implantation mechanism in Juniperus sabina. Tisserand & Young 2014 (B216) state verbatim: "Plectranthus, which is not commercially available, is the only essential oil known to be strongly teratogenic." No therapeutic benefit data exist. This profile is included solely as a class-reference for sabinyl-acetate reproductive toxicity to contextualize the safer commercial EOs in the same chemical class.
NarrativeTâm trạng: Stimulating, Grounding
Chakra
solar
Ngũ hành
moc
| Phương pháp | Liều lượng | Ghi chú |
|---|---|---|
| Diffusion / Aromatic inhalation | CONTRAINDICATED — no dose applicable | Non-commercial research-only oil. No safe inhalation dose established. Must not be diffused, especially near pregnant individuals. B216 Tisserand & Young 2014 Ch.11. |
| Topical application | CONTRAINDICATED — no safe dilution established | Contraindicated all routes in pregnancy and breastfeeding. No safe dilution established. B216 Ch.11: 'only EO known to be strongly teratogenic.' Non-commercial; no product exists. |
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Bảo quản
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