SYMELab
The Perfumer's Grimoire

Tinh dầu bạc hà Âu

Peppermint

Mentha × piperita L.

Top/MiddleLong não

The mát sắc sảo, bạc hà sắc bén, sạch sẽ thanh khiết, thảo mộc the lạnh, tỉnh táo

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Tóm Tắt Khoa Học

Từ Thư Viện Kinh Điển
  1. Mentha × piperita L. (Lamiaceae, hybrid of M. aquatica × M. spicata), leaves, steam distillation. "Peppermint / Bạc hà Âu" — the cornerstone high-menthol Lamiaceae; ISO standards split US vs non-US grades; frequently ADULTERATED with cornmint (M. arvensis — see [[cornmint]]) per Kubeczka 2002.
  2. Chemistry = menthol 19.0–54.2% + menthone 8.0–31.6% + menthyl acetate 2.1–10.6% + 1,8-cineole 2.9–9.7% + menthofuran tr–9.4% + pulegone 0.3–4.7%. Range ceiling values (B216) are wider than ISO standards (US pulegone 0.5–2.5% / non-US 0.5–3.0%; menthofuran 1.5–6.0% / 1.0–8.0%). T&Y safety calculations use ISO ceilings: 8.0% menthofuran + 3.0% pulegone.
  3. Hazards: Choleretic + neurotoxicity + mucous membrane irritation (low). Contraindications (ALL routes): cardiac fibrillation, G6PD deficiency, "do not apply to or near the face of infants or children." Contraindications (oral): cholestasis. Cautions (oral): GERD.
  4. Dual-driver numeric caps (CRITICAL): Dermal 5.4% (menthofuran 0.5% + pulegone 1.2% combined, mass-balance); Oral 152 mg/day (menthofuran 0.2 mg/kg/day + pulegone 0.5 mg/kg/day). Both caps from ISO ceilings. CI and dilution not aligned one-to-one — even at 5.4% dilution a G6PD-deficient person or cardiac-fibrillation patient must AVOID, not merely reduce dose. Layer 2.5 must encode both axes.
  5. Not phototoxic (Placzek 2007 in vitro). Not pregnancy-contraindicated explicitly but framework-cautious (pulegone + menthofuran hepatotoxicity). Cornmint (M. arvensis, menthol 59–85%) shares SAME safety profile — CI set + dual-driver pattern — and is frequently adulterant. Infants high-risk: Melis 1989 + Reynolds 1993 menthol + 1,8-cineole nasal instillation instant collapse + apnea pathway.
Tinh dầu bạc hà Âu (Peppermint)
Thận trọngNốt Top/MiddleCamphoraceous

Peppermint

Tinh dầu bạc hà Âu (Peppermint)

Mentha × piperita L.

Tinh dầu bạc hà Âu (Peppermint) — Camphoraceous

⚠️Tinh dầu này cần thận trọng khi sử dụng. Đọc kỹ hướng dẫn an toàn.

Tổng Quan

Danh pháp khoa học
Mentha × piperita L.
Họ thực vật
Lamiaceae
Bộ phận dùng
Lá và thân cây tươi / khô nhẹ trước khi chưng cất (aerial parts)
Phương pháp chiết xuất
Steam distillation (chưng cất lôi cuốn hơi nước)
Màu sắc
Colorless to pale yellow, mobile liquid
Phân loại nốt hương
Nốt Top/Middle
Hương thơm
Top-Middle note; intensely fresh, minty, cool-icy, slightly camphoraceous, clean herbal dry-out
Chemotype / Cultivar
Menthol CT (dominant, >35% menthol) — tiêu chuẩn thương mại; Carvone CT (M. piperita hiếm); Mitchell CT (high menthofuran — inferior quality). M. piperita là hybrid tự nhiên của M. aquatica × M. spicata

Các quốc gia sản xuất chính

USA (Pacific Northwest — Oregon, Washington, Idaho)IndiaChinaUKFrance

Tình trạng tại Việt Nam

Xem chi tiết

Phân loại nốt
Top-Middle
Cường độ
9/5
Độ bền trên da
2–4 giờ
Họ hương
Camphoraceous
Hương đầu (Opening)(0–15 phút)

Sharp minty, piercing peppermint, clean and pure, cold herbal, alerting

Hương giữa (Heart)(15–60 phút)

The mát sắc sảo, bạc hà sắc bén, sạch sẽ thanh khiết, thảo mộc the lạnh, tỉnh táo

Hương nền (Drydown)(1–4 giờ)

2–4 giờ

Cường độ hương
9/5
Da khô
2/5

Menthol + menthone drying effect; tránh dùng da khô; nếu dùng cần carrier nourishing

Da dầu/mụn
4/5

Antibacterial + astringent tốt; dùng ≤1% trong toner; menthol giảm bã nhờn

Da lão hóa
3/5

Vasodilatory tốt cho circulation; nhưng menthol drying — dùng thấp ≤0.5–1%

Da thường
4/5

Phù hợp tốt trong serum cooling, toner, body lotion ≤1–2%

Da nhạy cảm
2/5

Menthol có thể gây irritation, đỏ da; ≤0.5%; patch test bắt buộc

Da hỗn hợp
4/5

Phù hợp tốt cho vùng chữ T oily; tránh vùng má; ≤1%

Sản xuất tại VNImported Only

Tên gọi tại Việt Nam

Tinh dầu bạc hà Âu (còn gọi: tinh dầu bạc hà peppermint, bạc hà Anh)

Pha Chế & Hòa Hợp

Counterirritant / topical analgesic

Menthol (dominant constituent) selectively activates TRPM8 cold thermoreceptors in the skin, producing a cooling sensation that gates spinal nociceptive signalling and provides transient analgesic relief.

Ref: Tisserand & Young (2014) Essential Oil Safety 2nd ed, Ch.13 p.756–761

Antispasmodic / carminative

Menthol and menthone relax GI smooth muscle via calcium channel antagonism, reducing intestinal spasm, bloating, and flatulence.

Ref: Blumenthal et al. (1998) — Commission E monograph [via B216]; Tisserand & Young (2014) Ch.13

Choleretic

Oil constituents stimulate hepatic bile production and biliary flow; contraindicated in cholestasis because this same mechanism exacerbates bile duct obstruction.

Ref: Trabace et al. (1994); Fujii et al. (1994) [via B216]

Antioxidant / free radical scavenging

Phenolic and terpene constituents donate hydrogen atoms to free-radical chains; activity confirmed by DPPH radical scavenging assay.

Ref: Mimica-Dukic et al. (2003) [via B216]

Decongestant / nasal secretolytic

Inhaled menthol stimulates TRPM8 cold receptors in nasal mucosa, creating a subjective sensation of increased airway patency and facilitating easier breathing during congestion.

Ref: Tisserand & Young (2014) Ch.13 p.756–761

Antimicrobial (broad-spectrum)

Menthol and menthone interact with bacterial cell membrane phospholipid bilayers, compromising membrane integrity and inhibiting microbial growth across Gram+ and Gram− strains.

Ref: Tisserand & Young (2014) Ch.13; class-extrapolation from cornmint (Mentha arvensis)

Göbel et al. 1996 / Headache journal

10% peppermint EO in ethanol topical = acetaminophen 1000mg cho tension headache; n=32

RCT (cross-over)

Cochrane Review (Pittler & Ernst)

Enteric-coated peppermint oil superior to placebo for IBS — NNT = 2.5

Systematic Review / Meta-analysis

Kim et al. 2016 / Toxicol Res

3% peppermint oil promotes hair growth equivalent to 3% minoxidil in mice

Animal Controlled

CIR Expert Panel cir-safety

Peppermint oil safe in cosmetics when menthol content ≤ ADI 0.2mg/kg/day; pulegone ≤1%

Regulatory Review

Tâm trạng: Stimulating, Uplifting

focusclarityalertnessfatigueinvigorationoverwhelm

Chakra

Throat (Vishuddha)

Ngũ hành

Metal

Phương phápLiều lượngGhi chú
Diffusion (khuếch tán)3–5 drops / 100ml nước20–40 phút; phòng làm việc, phòng học; không khuếch tán lâu — menthol cao gây kích thích quá mức
Topical massage1–3% dilutionJojoba hoặc sweet almond; KHÔNG dùng quá 3% trên da mặt; headache roller 2%
Bath (tắm)3–5 drops pha trong 1 tsp carrier⚠️ Tránh bồn tắm nước nóng — menthol + steam quá mạnh; pha với sweet almond; kích thích, không thư giãn
Inhalation (hít)1–2 drops trên khăn / inhaler stick2–3 phút; focus/study; respiratory congestion
Skincare (chăm sóc da)0.5–1% trong serum/tonerCooling, tighten pores; KHÔNG dùng vùng mắt; tránh >1% trên da mặt nhạy cảm

Dầu nền phù hợp

JojobaLightweight, non-comedogenic wax ester ideal for peppermint spot-application and headache blends; absorbs cleanly without competing with menthol's cooling sensation.
Sweet almond oilNeutral scent and medium absorption complement peppermint's intensity; well-suited for full-body massage at 1–2% dilution.
Fractionated coconut oilFast-penetrating, non-greasy base matched for sports and post-exercise muscle blends where peppermint's counterirritant action is most useful.
Aloe vera gelAqueous gel base amplifies peppermint's cooling sensation and lowers skin surface temperature — effective vehicle for headache roll-ons at ≤1% dilution.

Kết hợp tốt với

CamphoraceousHerbaceousCitrusResinousEucalyptus-family

Blend kinh điển

Eucalyptus + Peppermintdouble TRPM8/camphoraceous effect; kinh điển cho respiratory blend, tiger balm-style
Lavender + Peppermintminty-floral; giảm đau đầu, headache roller blend đã có RCT evidence
Rosemary + Peppermintdual stimulating herbaceous; focus/study blend, hair scalp stimulation
Bergamot + Peppermintcitrus-fresh-minty; invigorating morning diffuser hoặc shower gel
[Primary safety] Tisserand & Young, Essential Oil Safety 2nd Ed. — Peppermint p. 360–362 [CITATION-NEEDED exact page confirm]
[CIR Safety] CIR Amended Safety Assessment — Mentha Piperita Oil — https://www.cir-safety.org/sites/default/files/peppermint.pdf cir-safety
[IFRA Certificate] NHR Organic Oils IFRA 49th Amendment Conformity Certificate — https://www.nhrorganicoils.com/uploads/20211109101904e_Peppermint_IFRA_49.pdf nhrorganicoils
[IFRA (Amphora)] Amphora Aromatics IFRA Peppermint Organic — https://www.amphora-aromatics.com/images/product/271%20IFRA%20Peppermint%20Organic%20Oil%20-%20Version%201.pdf amphora-aromatics
[Chemistry / Spec] NHR Organic Oils Product Specification — https://www.nhrorganicoils.com/uploads/20211104143042e_Peppermint_Spec.pdf nhrorganicoils
[Chemistry / COA] Madar Corporation COA — https://www.madarcorporation.com/spec-sheets/essential-oil/piperita-mentha/Piperita%20Mentha%20-%204526511%20All%20docs.pdf madarcorporation
[FEMA / CAS] FEMA Flavor Library — FEMA 2848 — https://www.femaflavor.org/flavor-library/peppermint-oil-mentha-piperita-l femaflavor
[FDA GRAS] FDA FCID — CAS 8006-90-4 GRAS — https://hfpappexternal.fda.gov/scripts/fdcc/index.cfm?set=FoodSubstances&id=PEPPERMINTOILMENTHAPIPERITA hfpappexternal.fda
[Physical data] ScenTree — Mentha piperita oil — https://www.scentree.co/en/Mentha_piperita_oil.html scentree
[VN Context] Liên Minh Xanh — Các loài bạc hà — https://www.lienminhxanh.com/tinh-dau-bac-ha/ lienminhxanh
[VN Context 2] Kepha.vn — Tinh dầu bạc hà Âu — https://kepha.vn/kien-thuc/loi-ich-va-cong-dung-tinh-dau-bac-ha-au kepha
[Data reliability] HIGH — CAS/FEMA/INCI từ nguồn chính thức FDA/FEMA; IFRA limits từ certificate thực; GC/MS từ NHR COA; CIR safety từ nguồn regulatory; clinical evidence từ Cochrane + Göbel RCT được công nhận rộng rãi

An Toàn

Giới hạn da tối đa

5.9%

Giới hạn IFRA

Yes — restricted via constituent Carvone (QRA) và Limonene, Linalool (specification standard)

Thai kỳ & Cho con bú

Tam cá nguyệt 1AVOID
Tam cá nguyệt 21.0%
Tam cá nguyệt 31.0%

Giới hạn độ tuổi

AVOID

Bảo quản

_conditions: Cool, dark, airtight. No refrigeration required; stable oil oxidation_risk: Medium ``` Lưu ý vận chuyển: Flash point 70°C → trên ngưỡng IATA Class 3 (<60°C); peppermint EO KHÔNG phải Dangerous Goods Class 3 — an toàn vận chuyển hàng không thông thường scentree `oxidation_risk: Medium` —

Thông tin chỉ mang tính tham khảo, không thay thế tư vấn y tế chuyên nghiệp. SYMELab v2.0

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Hồ Sơ Hoá Học Chi Tiết
§3 Chemical Profile — chemotype, constituent ranges, adulteration

Overall range (B216 aggregate):

Constituent%
(−)-Menthol19.0–54.2%
Menthone8.0–31.6%
(−)-Menthyl acetate2.1–10.6%
Neomenthol2.6–10.0%
1,8-Cineole2.9–9.7%
(6R)-(+)-Menthofurantr–9.4%
Isomenthone2.0–8.7%
Terpinen-4-ol0–5.0%
(1R)-(+)-β-Pulegone0.3–4.7%
(+)-Limonene0.8–4.5%
Germacrene Dtr–4.4%
β-Caryophyllene0.1–2.8%
(E)-Sabinene hydrate0.2–2.4%
β-Pinene0.6–2.0%
Piperitone0–1.3%
Isomenthol0.2–1.2%

ISO — US oil:

Constituent%
(−)-Menthol36.0–46.0%
Menthone15.0–25.0%
(−)-Menthyl acetate3.0–6.5%
1,8-Cineole4.0–6.0%
Menthofuran1.5–6.0%
Isomenthone2.0–4.5%
β-Pulegone0.5–2.5%

ISO — non-US oil:

Constituent%
(−)-Menthol32.0–49.0%
Menthone13.0–28.0%
(−)-Menthyl acetate2.0–8.0%
1,8-Cineole3.0–8.0%
Menthofuran1.0–8.0%
Isomenthone2.0–8.0%
β-Pulegone0.5–3.0%

Chemistry insight:

  • T&Y uses ISO ceilings (8.0% menthofuran + 3.0% pulegone) for safety-cap calculation because these represent commercially traded oils. Actual UK-market 1996 JFSSG survey found pulegone 0.2–2.9%.
  • Menthol is peppermint's "active pharmacological ingredient" (Sidell 1990) — CNS effect profile + cardiac calcium-channel block + G6PD-metabolized detoxification pathway.
  • Menthofuran + pulegone = hepatotoxicity drivers (Madyastha & Raj 1994 rat hepatotoxicity menthofuran 250 mg/kg/day × 3 days; β-pulegone profile Ch.14 hepatotoxic).
  • Menthone + menthol platelet aggregation inhibition (Murayama & Kumaroo 1986) — very weak, not clinically significant.
  • Pulegone content varies by soil + harvest time (Farley & Howland 1980). Some historical reports 8–9% (NOT representative of modern traded oil).
  • Adulteration fingerprint: Cornmint (M. arvensis) has menthol 59–85% + menthone 9–22%; overlap with peppermint menthol range but cornmint lacks the menthofuran signature.
Công Dụng Trị Liệu Chi Tiết
§10 Therapeutic Uses — skin, emotional, physical, respiratory
  • IBS (irritable bowel syndrome): Enteric-coated peppermint oil capsules — CLINICALLY validated via RCTs outside B216 scope (e.g. Cash 2016 meta-analysis). 0.2–0.4 mL × 3/day enteric-coated = established GP prescription. Spasmolytic mechanism via calcium-channel block on intestinal smooth muscle.
  • Nasal congestion / headache: Topical forehead/temple 1–3% carrier dilution (tension-type headache — Göbel 1994 + 1996 clinical — outside B216); inhalation for sinus congestion.
  • Mental alertness / fatigue: Classic workplace / cognitive-task aromatherapy.
  • Antipruritic: Topical menthol cooling effect for pruritus.
  • Musculoskeletal: Diluted muscle rub (avoid cardiac-fibrillation / G6PD patients even topical).
  • Oral + dental: Flagship commercial use — toothpaste, mouthwash, confectionery (sub-therapeutic doses).
  • Antimicrobial / antifungal: Broad-spectrum menthol signal.
Năng Lượng & Ngũ Hành
§11 Energetics — TCM, Ayurveda, aromatic energetics
  • Five-element: Kim (Metal — lung, cooling-dispersing) + Mộc (Wood — liver-qi, disperses Heat).
  • TCM: Cools Heat; disperses Wind-Heat; clears Head + Throat; traditional for headache + sore throat + Wind-Heat invasion (classical Bò hà formulas, often combined with chrysanthemum + kudzu). Ayurveda: pacifies Pitta + Kapha; aggravates Vata at high dose (cooling excess).

Dữ Liệu Kỹ Thuật Y Khoa

§14 Renderer Contract — Tisserand & Young V2.2

Thông Số Định Lượng

hazards
["choleretic","neurotoxicity_dose_dependent","mucous_membrane_irritation_low","cardiac_fibrillation_risk_menthol","G6PD_deficiency_risk_menthol"]
phototoxic
false
caution_GERD_oral
true
drug_interactions
[]
contraindicated_G6PD
true
max_dilution_elderly
3
max_oral_dose_mg_day
152
max_dilution_child_2_6
0.5
max_dilution_adult_face
2
max_dilution_child_6_12
2
contraindicated_pregnancy
false
max_dilution_child_under2
max_dilution_adult_general
5.4
max_dilution_breastfeeding
2
max_dilution_pregnancy_1st
1
max_dilution_pregnancy_2nd
2
max_dilution_pregnancy_3rd
2
contraindicated_breastfeeding
false
max_oral_dose_mg_day_pregnancy
contraindicated_children_under2
true
contraindicated_cholestasis_oral
true
contraindicated_cardiac_fibrillation
true

Luận Giải Văn Cảnh

quality_notes

'Adulteration with cornmint common; verify via menthofuran + pulegone GC peaks

drug_interactions

] OR ['CYP3A4_high_dose_only

oral_contraindications

cholestasis']; oral_cautions: ['GERD

max_dilution_adult_general

5

Tài Liệu Y Khoa Tham Khảo

  • Tisserand & Young (2014) Essential Oil Safety 2nd ed — Ch.13 p.756–761
  • Lawrence (1993 p.31–35, 1995g p.94–105, 1997d p.57–66) — GC profile [via B216]
  • © ISO 2006 — US + non-US peppermint standards [via B216]
  • Kubeczka (2002) — cornmint adulteration [via B216]
  • Thomas (1962) — quinidine cardiac fibrillation trigger [via B216]
  • Olowe & Ransome-Kuti (1980) — G6PD neonatal jaundice umbilical-stump menthol [via B216]
  • Melis et al. (1989); Reynolds (1993) — infant nasal-instillation apnea + collapse [via B216]
  • Trabace et al. (1994); Fujii et al. (1994) — choleretic + cholestasis CI [via B216]
  • Thorup et al. (1983a); Olsen & Thorup (1984); Spindler & Madsen (1992); Mengs & Stotzem (1989); Eickholt & Box (1965) — neurotoxicity NOAEL [via B216]
  • O'Mullane et al. (1982) — human acute inhalation toxicity [via B216]
  • Gordon et al. (1982); Madyastha & Raj (1994); Vo et al. (2003); Madsen et al. (1986); Mølck et al. (1998) — hepatotoxicity constituent / whole-oil [via B216]
  • Murayama & Kumaroo (1986); Teuscher et al. (1989); De Smet et al. (1992); Schafer et al. (1986); Hills & Aaronson (1991); Sidell et al. (1990) — cardiac + CNS [via B216]
  • Placzek et al. (2007) — non-phototoxic in vitro [via B216]
  • Meneghini et al. (1971); Rudzki et al. (1976); Santucci et al. (1987); Frosch et al. (2002b); Paulsen & Andersen (2005); Wöhrl et al. (2001); Uter et al. (2010); Kanerva et al. (2001a); De Groot (1987); Selvaag et al. (1995); Parys (1983); Peltonen et al. (1985) — dermatitis patch series [via B216]
  • Morton et al. (1995); Rogers & Pahor (1995); Fleming & Forsyth (1998) — oral mucous membrane reports [via B216]
  • Mimica-Dukic et al. (2003); Dresser et al. (2002) — DPPH + antioxidant + CYP3A4 inhibition [via B216]
  • Andersen & Jensen (1984); Ishidate et al. (1984); Lazutka et al. (2001); Heck et al. (1989); Lam & Zheng (1991); Sharafi et al. (2010); Franzios et al. (1997); Stoner et al. (1973) — carcinogenicity/mutagenicity series [via B216]
  • Wacher et al. (2002); Samojlik et al. (2012); Abdullah et al. (1996); Nielsen (2006) — drug interaction series [via B216]
  • Farley & Howland (1980); Joint Food Safety and Standards Group UK 1996 — pulegone variability + commercial survey [via B216]
  • Blumenthal et al. (1998) — Commission E monograph dose guidance [via B216]
  • Nair (2001b) — CIR pulegone 1.0% cosmetic cap [via B216]
  • Gaworski et al. (1994) — massive-dose immunotoxicity [via B216]