SYMELab
Trang chủThư Viện HươngMyrtle (bog), Sweet gale, Bog myrtle
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Tinh dầu sim đầm lầy

Myrtle (bog), Sweet gale, Bog myrtle

Myrica gale L.

Top/MiddleNhựa thơm

Hương nhựa-balsamic, hương lá ngọt-tươi, β-caryophyllene gỗ-cay, β-myrcene nhựa thông, limonene cam tươi, hơi long não, hương đầm lầy, vương vấn bạch đàn, đặc trưng chiết xuất Canada, chemotype sạch Myrica gale

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Tóm Tắt Khoa Học

Từ Thư Viện Kinh Điển

Bog myrtle / sweet gale essential oil (Myrica gale L., Myricaceae — bayberry family per modern APG-IV taxonomy; CRITICAL B216 family typo rail: B216 EXPLICIT verbatim p.711 lists "Family: Myrtaceae" but Myrica gale is taxonomically placed in Myricaceae family per APG-IV, NOT Myrtaceae — common-name "myrtle" is misleading nomenclatural collision because true myrtle Myrtus communis IS Myrtaceae but Myrica gale is a distinct genus Myrica in family Myricaceae sister-clade to Betulaceae+Casuarinaceae per modern molecular phylogenetics; B216 family designation is outdated taxonomy — flag WIKI_WEB_CONFLICT:plant_family) is a sesquiterpene-DOMINANT clean leaf-distilled EO with B216-T&Y "None known × 2" hazard signature + Canadian-only commercial origin per Lawrence/Mainguy chemistry. B216 Ch.13 p.711 cites Mainguy (private communication 2001) chemistry: β-Caryophyllene 11.0% (major-dominant) + β-Myrcene 9.5% (secondary) + (+)-Limonene 7.2% (tertiary) + δ-Cadinene 4.7% + α-Caryophyllene 4.4% + α-Phellandrene 4.2% + Germacrone 3.7% + γ-Elemene 3.3% + α-Cadinol + unidentified 2.9% + α-Selinene 2.6% + p-Cymene 2.5% + (E)-β-Ocimene 2.3% + α-Longipinene 1.7% + (Z)-β-Ocimene 1.7% + Selin-11-en-4-ol 1.7% + (E)-Nerolidol 1.5% + Caryophyllene oxide 1.2% + 1,8-Cineole 1.1% + α-Bisabolol 1.0%. Hazard signature B216 EXPLICIT verbatim: "Hazards: None known. Contraindications: None known." Adverse-skin-reactions data-gap rail B216 EXPLICIT verbatim: "No information found." Acute-toxicity-data-gap rail B216 EXPLICIT verbatim: "No information found." Anticarcinogenic-class rail B216 EXPLICIT verbatim: A bog myrtle oil hydrodistilled in Canada and containing 12.1–23.2% myrcene, 6.8–11.2% (+)-limonene, 9.3–11.0% β-caryophyllene and 6.5–9.9% α-phellandrene demonstrated anticarcinogenic activity against human lung carcinoma (A-549) and human colon adenocarcinoma cell lines (Sylvestre et al 2005); β-caryophyllene + α-caryophyllene + (+)-limonene class-shared anticarcinogenic-activity per B216 Chapter 14 constituent profiles; α-cadinol active against human colon cancer cells (He et al 1997a); germacrone active against human breast cancer cells (Zhong et al 2011). Comments + commercial-niche + insect-repellent reputation B216 EXPLICIT verbatim: "The plant, which has a reputation for repelling small flying insects, grows in many parts of the world, but the oil is only distilled in Canada. Limited availability." → CRITICAL Canadian-only commercial-distillation rail = species M. gale has circumboreal distribution (UK + Northern Europe + Russia + North America boreal wetlands) but commercial EO production confined to Canada per B216 EXPLICIT. Sesquiterpene-DOMINANT class-rail: total sesquiterpene-class constituents ≈ 35% combined (β-caryophyllene + α-caryophyllene + δ-cadinene + germacrone + γ-elemene + α-cadinol + α-selinene + α-longipinene + (E)-nerolidol + caryophyllene oxide + α-bisabolol + selin-11-en-4-ol) class-shared with [[muhuhu]] EO772 26a (Asteraceae α-amorphene 16.5% MAJOR-DOM ~76% sesquiterpene combined) + [[copaiba]] EO710 16c (β-caryophyllene resin) + cedarwood-class. Latent-monoterpene-oxidation-precaution rail: β-myrcene 9.5% + (+)-limonene 7.2% + α-phellandrene 4.2% + p-cymene 2.5% + (E)-β-ocimene + (Z)-β-ocimene 4.0% combined ~27.4% combined monoterpene-class — class-shared latent-oxidation precaution rail with [[hemp]] EO739 21a β-myrcene 21–31% + [[lemon-balm]] EO759 23c (+)-limonene latent-oxidation T&Y EXPLICIT mandatory refrigerated rail; storage cool-dark-airtight + antioxidant-class precaution. Anticarcinogenic-class rail: M. gale leaf EO is a documented anticarcinogenic-class anchor oil (Sylvestre et al 2005 Phytomedicine 12:299–304) — class-rail with [[lantana]] EO754 23b davanone 90-day clean (Oser 1965) + cluster of β-caryophyllene anticarcinogenic-class peers per T&Y Ch.14 verbatim. Bog-myrtle-vs-true-myrtle (Myrtus communis) cross-genus species-disambiguation rail: Myrica gale (this oil — Myricaceae, sesquiterpene + monoterpene mixed) vs Myrtus communis "true myrtle" (Myrtaceae, α-pinene + 1,8-cineole or myrtenyl-acetate-CT cineole-CT); not the same species + not the same family despite shared "myrtle" common name; species-disambiguation parallels [[lemon-balm]] EO759 23c Eucalyptus staigerianaMelissa officinalis false-cognate-common-name rail. Continues Mini-Batch 26b after 26a CLOSED.

🌿
Thận trọngNốt Top/MiddleResinous-balsamic

Myrtle (bog), Sweet gale, Bog myrtle

Tinh dầu sim đầm lầy (sweet gale)

Myrica gale L.

Tinh dầu sim đầm lầy (sweet gale) — Resinous-balsamic

⚠️Tinh dầu này cần thận trọng khi sử dụng. Đọc kỹ hướng dẫn an toàn.

Tổng Quan

Danh pháp khoa học
Myrica gale L.
Họ thực vật
Myricaceae
Bộ phận dùng
Leaves
Phương pháp chiết xuất
steam_distillation
Màu sắc
Phân loại nốt hương
Nốt Top/Middle
Hương thơm
Chemotype / Cultivar

Các quốc gia sản xuất chính

Canada

Tình trạng tại Việt Nam

Xem chi tiết

Phân loại nốt
Top-Middle
Cường độ
3/5
Độ bền trên da
2–4 giờ
Họ hương
Resinous-balsamic
Hương đầu (Opening)(0–15 phút)

Resinous-balsamic, sweet-fresh-leaf, β-caryophyllene-woody-spicy, β-myrcene-resinous, limonene-citrus-fresh, mildly-camphoraceous, bog-wetland-herbal, slight-eucalyptus-undertone, Canadian-distilled-niche, Myrica gale clean-class

Hương giữa (Heart)(15–60 phút)

Hương nhựa-balsamic, hương lá ngọt-tươi, β-caryophyllene gỗ-cay, β-myrcene nhựa thông, limonene cam tươi, hơi long não, hương đầm lầy, vương vấn bạch đàn, đặc trưng chiết xuất Canada, chemotype sạch Myrica gale

Hương nền (Drydown)(1–4 giờ)

2–4 giờ

Cường độ hương
3/5
Da khô
3/5

Da dầu/mụn
3/5

Da lão hóa
3/5

Da thường
3/5

Da nhạy cảm
2/5

Da hỗn hợp
3/5

Nhập khẩuImported

Tên gọi tại Việt Nam

Tinh dầu sim đầm lầy (sweet gale)

Pha Chế & Hòa Hợp

Anti-inflammatory (CB2-mediated, class-extrapolation)

β-Caryophyllene (11.0%) acts as a selective CB2 cannabinoid receptor agonist, modulating NF-κB inflammatory signalling and reducing pro-inflammatory cytokine expression.

Ref: class-extrapolation from β-caryophyllene; B216 Ch.14 β-Caryophyllene profile (Tisserand & Young 2014)

Anticarcinogenic — lung/colon (in vitro)

Whole Canadian bog myrtle EO demonstrated cytotoxic activity against A-549 lung adenocarcinoma and colon adenocarcinoma cell lines in vitro; chemistry profile varied with distillation time fraction.

Ref: Sylvestre et al 2005, Phytomedicine 12:299–304

Anticarcinogenic — colon (α-cadinol, in vitro)

α-Cadinol, a sesquiterpene alcohol present in bog myrtle EO, demonstrated specific activity against the human HT-29 colon cancer cell line in vitro.

Ref: He et al 1997a

Anticarcinogenic — breast (germacrone, in vitro)

Germacrone, a sesquiterpene ketone identified in bog myrtle EO, demonstrated activity against human breast cancer cells in vitro.

Ref: Zhong et al 2011

Insect repellent

Traditional folk use across the circumboreal range of Myrica gale as an insect deterrent; volatile sesquiterpene and monoterpene fractions confer repellent properties explicitly recognised by B216.

Ref: Tisserand & Young 2014, Ch.13 p.711

Anxiolytic / calming (class-extrapolation)

β-Caryophyllene (11.0%) class-level anxiolytic activity via CB2 receptor engagement; β-myrcene (9.5%) contributes secondary sedative-calming tone at the monoterpene level.

Ref: class-extrapolation from β-caryophyllene; B216 Ch.14 β-Caryophyllene profile (Tisserand & Young 2014)

AI-summary

No RCT-grade clinical trial evidence is available for myrtle-bog (Myrica gale) essential oil. The strongest available evidence is in vitro: Sylvestre et al (2005, Phytomedicine 12:299–304) demonstrated cytotoxicity of Canadian-distilled bog myrtle EO against A-549 lung adenocarcinoma and colon adenocarcinoma cell lines, with chemistry varying by distillation time fraction. Constituent-level in-vitro evidence includes He et al (1997a) confirming α-cadinol activity against HT-29 colon cancer cells, and Zhong et al (2011) confirming germacrone activity against breast cancer cells. All anticarcinogenic references are research context only and do NOT constitute therapeutic claims. Insect-repellent use is traditional folk use without controlled clinical study citation in B216. B216 records a triple safety data gap: no skin-sensitisation, acute toxicity, or carcinogenicity data found.

Narrative

Tâm trạng: Grounding, Balancing

protectionresiliencegroundingwildnessclarityinner-stillness

Chakra

root

Ngũ hành

moc

Phương phápLiều lượngGhi chú
Diffusion3-5 drops in 100 ml diffuser waterForest-green balsamic aroma; limit session to 30–60 min, ventilate between. Limited global availability makes diffusion the most cost-efficient delivery route.
Topical massage1-2.5% in carrier oil (max 5% adult, framework default)Stay within 5% adult max dermal (B216 framework default). Patch-test recommended; triple safety data gap. Avoid oxidised oil — refrigerate stock and use antioxidant-stabilised batches.
Skincare application0.5-1% in unscented base (leave-on); up to 2% rinse-offConservative dilution due to absence of skin-sensitisation data. β-Caryophyllene anti-inflammatory class-extrapolation may suit mature or inflamed skin. Avoid hypersensitive/damaged skin.
Direct inhalation1-2 drops on tissue or 3-4 drops in steam bowlSteam bowl: inhale 5–10 min, eyes closed. Tissue: intermittent use. Supports respiratory comfort and grounding aromatherapy.
Insect-repellent formulation2-3% in light carrier oil or unscented lotionTraditional folk use as insect deterrent within 5% max dermal cap. Reapply as needed. No controlled efficacy data available; complementary use only.

Dầu nền phù hợp

Jojoba oilLiquid wax with excellent oxidative stability, ideal for latent monoterpene autoxidation risk (β-myrcene + limonene); non-comedogenic, suits all skin types.
Fractionated coconut oilLong shelf-life saturated carrier reduces oxidation risk; lightweight, odourless base preserves delicate balsamic-green aroma; even dispersion of mixed sesquiterpene-monoterpene profile.
Sweet almond oilBalanced oleic/linoleic profile with mild skin-conditioning properties; compatible with anti-inflammatory sesquiterpene class; suitable for 1–2.5% massage blends.

Kết hợp tốt với

ResinousSpicyHerbaceousEarthyGreen

Blend kinh điển

[B216] Ch.13 p.711 Myrtle (bog) profile (primary source)
[Mainguy 2001] Myrica gale essential oil chemistry profile (cited in B216 Ch.13 p.711)
[Sylvestre et al 2005] Phytomedicine 12:299–304 Canadian bog myrtle oil anticarcinogenic chemistry vs A-549 + colon adenocarcinoma + distillation-time variance
[He et al 1997a] α-cadinol active human colon cancer cells
[Zhong et al 2011] germacrone active human breast cancer cells
[B216 β-Caryophyllene profile Chapter 14] anticarcinogenic-class profile
[B216 β-Myrcene profile Chapter 14] latent-autoxidation precaution-class
[APG-IV] Myricaceae family taxonomic placement modern molecular phylogenetics

An Toàn

Giới hạn da tối đa

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Giới hạn IFRA

Xem chi tiết

Thai kỳ & Cho con bú

Tam cá nguyệt 1Unknown
Tam cá nguyệt 2Unknown
Tam cá nguyệt 3Unknown

Giới hạn độ tuổi

Xem chi tiết

Bảo quản

Bảo quản nơi tối, mát

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Hồ Sơ Hoá Học Chi Tiết
§3 Chemical Profile — chemotype, constituent ranges, adulteration

Per Mainguy (private communication 2001) cited in B216 Ch.13 p.711:

Constituent%Role
β-Caryophyllene11.0%Major-dominant — bicyclic sesquiterpene (C15H24, caryophyllane skeleton); woody-spicy character; class-shared with [[copaiba]] EO710 16c β-caryophyllene-resin + [[blackcurrant-bud]] EO690 14b + [[lantana]] EO754 23b 12% + many leaf-EOs; T&Y Ch.14 anticarcinogenic-class profile
β-Myrcene9.5%Secondary — acyclic monoterpene (C10H16); resinous-balsamic character; latent-autoxidation-class precaution rail; class-shared with [[hemp]] EO739 21a 21–31% + [[grindelia]] EO736 20b 14–26% + many monoterpene-EOs
(+)-Limonene7.2%Tertiary — monocyclic monoterpene; citrus-fresh character; T&Y Ch.14 IFRA 2009 peroxide-control class-rail (BHT/α-tocopherol 0.1% at-production); anticarcinogenic-class profile per T&Y Ch.14
δ-Cadinene4.7%Bicyclic sesquiterpene (cadinane skeleton); class-shared with [[hinoki-wood]] EO743 21b cadinane-class peer + [[cypress-blue]] EO711 16c
α-Caryophyllene4.4%Sesquiterpene isomer of β-caryophyllene (humulene); anticarcinogenic-class T&Y Ch.14
α-Phellandrene4.2%Monocyclic monoterpene; peppery-citrus; latent-oxidation-precaution-class
Germacrone3.7%Sesquiterpene ketone (germacrane skeleton); anticarcinogenic-class per Zhong 2011 human breast cancer cells active
γ-Elemene3.3%Sesquiterpene (elemane skeleton); class-shared with myrrh + minor-class wood EOs
α-Cadinol + unidentified2.9%Sesquiterpenoid alcohol (cadinane skeleton); anticarcinogenic-class per He 1997a active vs human colon cancer cells
α-Selinene2.6%Sesquiterpene (selinane skeleton)
p-Cymene2.5%Aromatic monoterpene; latent-oxidation-class minor
(E)-β-Ocimene2.3%Acyclic monoterpene; floral-green character; class-shared with [[jonquil]] EO748 22b 35.3% + [[laurel-berry]] EO757 23c 23.7%
α-Longipinene1.7%Tricyclic sesquiterpene (longipinane skeleton); class-rare-skeleton minor
(Z)-β-Ocimene1.7%Acyclic monoterpene Z-isomer
Selin-11-en-4-ol1.7%Sesquiterpenoid alcohol (selinane skeleton)
(E)-Nerolidol1.5%Sesquiterpenoid alcohol (acyclic); class-shared with niaouli/cabreuva
Caryophyllene oxide1.2%Sesquiterpenoid epoxide (caryophyllane skeleton oxidized)
1,8-Cineole1.1%Bicyclic monoterpenoid ether; minor — does NOT trigger children-face-CONTRA-class threshold (cineole 30%+ rail)
α-Bisabolol1.0%Sesquiterpenoid alcohol; anti-inflammatory class-shared with chamomile-German

Sesquiterpene-class combined ≈ 35% (β-caryophyllene 11.0% + α-caryophyllene 4.4% + δ-cadinene 4.7% + germacrone 3.7% + γ-elemene 3.3% + α-cadinol 2.9% + α-selinene 2.6% + α-longipinene 1.7% + selin-11-en-4-ol 1.7% + (E)-nerolidol 1.5% + caryophyllene oxide 1.2% + α-bisabolol 1.0%).

Monoterpene-class combined ≈ 27% (β-myrcene 9.5% + (+)-limonene 7.2% + α-phellandrene 4.2% + p-cymene 2.5% + (E)-β-ocimene 2.3% + (Z)-β-ocimene 1.7% + 1,8-cineole 1.1%) — latent-autoxidation precaution-class rail (β-myrcene + limonene + α-phellandrene + ocimene = monoterpene-oxidation-cluster).

Canadian distillation chemistry variance per Sylvestre 2005: A separately reported Canadian hydrodistilled bog myrtle oil contained myrcene 12.1–23.2% + (+)-limonene 6.8–11.2% + β-caryophyllene 9.3–11.0% + α-phellandrene 6.5–9.9% (different distillation times 30 min vs 60 min); the 60-minute fraction had higher sesquiterpene content. Distillation-time chemotype-variance rail.

No-thujone, no-camphor, no-pulegone, no-methyleugenol-class concern per Mainguy 2001 chemistry profile silence on these 4 hazard-class constituents — clean anticarcinogenic-class profile.

Anticarcinogenic-class rail B216 EXPLICIT verbatim: β-caryophyllene + α-caryophyllene + (+)-limonene class-shared anticarcinogenic-activity per Chapter 14 constituent profiles; α-cadinol active against human colon cancer cells (He et al 1997a); germacrone active against human breast cancer cells (Zhong et al 2011); whole-oil active against A-549 + colon adenocarcinoma per Sylvestre 2005.

Công Dụng Trị Liệu Chi Tiết
§10 Therapeutic Uses — skin, emotional, physical, respiratory

Per B216 + Northern European traditional + modern aromatherapy:

  • Insect-repellent / mosquito-deterrent (B216 EXPLICIT verbatim "reputation for repelling small flying insects" — historical PLANT use traditional Highland Scottish + Scandinavian + boreal-Indigenous-American midge-repellent application; modern EO use in insect-repellent formulations; class-shared with citronella/lemongrass/eucalyptus-cineole insect-repellent class)
  • Antimicrobial / antifungal (in-vitro from sesquiterpene-class + (+)-limonene-class)
  • Anticarcinogenic-class research (B216 EXPLICIT documented in-vitro activity Sylvestre 2005 + Zhong 2011 + He 1997a — clinical translation NOT established; research-class anchor only)
  • Skin-soothing / wound-supportive (modern aromatherapy class-rail with sesquiterpene-rich leaf EOs; α-bisabolol 1.0% + germacrone class-rail anti-inflammatory; data-gap class for whole-oil specifically)
  • Northern European traditional folk-medicine (Scotland Highland gruit beer-flavoring medieval pre-hop era + Scandinavian sweat-bath aromatic use centuries + Indigenous First Nations boreal-North-America Cree + Algonquin + Mi'kmaq insect-repellent + traditional smoke-fumigation; CRITICAL: PLANT use NOT concentrated EO; cultural-respect rail mandatory)
  • Vietnamese aromatherapy context: Tinh dầu sim đầm lầy (Myrica gale L. — chi Myrica họ Myricaceae KHÔNG PHẢI họ Myrtaceae mặc dù tên thường gọi "myrtle" — CẢNH BÁO PHÂN LOẠI — họ Myricaceae là họ riêng biệt với Myrtaceae trong APG-IV; B216 ghi nhầm họ Myrtaceae là lỗi đánh máy / phân loại lỗi thời) là tinh dầu β-caryophyllene 11.0% chiếm ưu thế chính + β-myrcene 9.5% phụ + (+)-limonene 7.2% bậc ba + sesquiterpene-class ~35% combined + monoterpene-class ~27% combined chiết xuất từ lá. Hồ sơ an toàn: B216 KHÔNG GHI NHẬN nguy hại × 2 — dữ liệu da liễu thiếu (no information found); KHÔNG quang độc; anticarcinogenic-class research-anchor (β-caryophyllene + α-caryophyllene + limonene + α-cadinol + germacrone + whole-oil documented in-vitro); B216 EXPLICIT "Limited availability". CRITICAL Canada-only-distillation-rail: Loài có phân bố toàn cầu boreal-wetland nhưng chỉ chiết xuất tinh dầu thương mại tại Canada. CRITICAL myrtle-vs-myrtle-vs-myrtle nomenclatural-collision-rail: M. gale (oil này — Myricaceae) ≠ Myrtus communis "myrtle thật" (Myrtaceae α-pinene+cineole) ≠ Backhousia citriodora [[myrtle-lemon]] EO776 cùng batch (Myrtaceae citral-cap-0.7%) ≠ Backhousia anisata myrtle-aniseed (Myrtaceae estragole-IFRA-cap). T&Y framework cap 5% người lớn (giảm cap mặt+nhạy cảm 2.5%); thai kỳ 2.5%; bảo quản lạnh khuyến cáo do β-myrcene + limonene latent-autoxidation. Tiếp tục Mini-Batch 26b sau 26a CLOSED.
Năng Lượng & Ngũ Hành
§11 Energetics — TCM, Ayurveda, aromatic energetics
  • Five Element: Wood (boreal-wetland-leaf class; mixed sesquiterpene-monoterpene); Water (bog/wetland habitat; cool-fresh-balsamic character)
  • Chakra: Heart (4th) — β-caryophyllene + α-caryophyllene + α-bisabolol soothing class; Solar plexus (3rd) — limonene-citrus-fresh activating class
  • Ayurvedic: Kapha-balancing via warming-spicy β-caryophyllene class; Vata-soothing via grounding sesquiterpene-class; Pitta-clearing via cool-fresh limonene class
  • TCM: Wood + Water elements; spirit-supporting via insect-repellent ancestral protective class-rail
  • Mood: Refreshing + protective + grounding per mixed-class profile
  • Heritage: Northern European + Boreal North American boreal-wetland heritage centuries traditional folk-use — Scottish Highland gruit beer pre-hop era + Scandinavian sweat-bath aromatic + Russian boreal traditional + Indigenous First Nations boreal-North-America (Cree + Algonquin + Mi'kmaq + Ojibwe boreal cultures) insect-repellent + smoke-fumigation + spiritual-protective ancestral applications; CRITICAL: PLANT use NOT concentrated EO — modern EO from Canadian-distillation only is recent commercial development; cultural-respect rail mandatory (Indigenous First Nations heritage); modern niche aromatherapy clean-class rail.

Dữ Liệu Kỹ Thuật Y Khoa

§14 Renderer Contract — Tisserand & Young V2.2

Thông Số Định Lượng

hazards
["hazards_none_known_TY_EXPLICIT_VERBATIM_p711","contraindications_none_known_TY_EXPLICIT_VERBATIM_p711","no_information_found_adverse_skin_reactions_data_gap_TY_EXPLICIT_p712","no_information_found_acute_toxicity_data_gap_TY_EXPLICIT_p712","anticarcinogenic_class_documented_sylvestre_2005_phytomedicine_a549_lung_carcinoma_colon_adenocarcinoma","beta_caryophyllene_11_pct_MAJOR_DOMINANT_anticarcinogenic_class","beta_myrcene_9_5_pct_secondary_latent_oxidation_precaution_class","limonene_7_2_pct_tertiary_IFRA_peroxide_control_anticarcinogenic_class","sesquiterpene_class_35_pct_combined","monoterpene_class_27_pct_combined_latent_autoxidation_precaution","alpha_cadinol_anticarcinogenic_he_1997a","germacrone_anticarcinogenic_zhong_2011","canadian_only_commercial_distillation_TY_EXPLICIT_p712","limited_availability_commercial_niche_TY_EXPLICIT_p712","insect_repellent_reputation_TY_EXPLICIT_p712","myricaceae_family_NOT_myrtaceae_apg_iv_taxonomic_correction_b216_typo_p711","distillation_time_chemotype_variance_sylvestre_2005_30min_vs_60min","no_thujone_no_camphor_no_pulegone_no_methyleugenol_clean_class"]
phototoxic
false
safety_level
caution
cap_derivation
framework_default_5pct_T_AND_Y_clean_HAZARDS_NONE_KNOWN_PLUS_CONTRAINDICATIONS_NONE_KNOWN_PLUS_TY_NO_INFORMATION_FOUND_DATA_GAP_PLUS_BETA_CARYOPHYLLENE_11_PCT_MAJOR_DOMINANT_PLUS_BETA_MYRCENE_9_5_PCT_PLUS_LIMONENE_7_2_PCT_PLUS_SESQUITERPENE_CLASS_35_PCT_COMBINED_PLUS_MONOTERPENE_CLASS_27_PCT_COMBINED_LATENT_OXIDATION_PRECAUTION_PLUS_ANTICARCINOGENIC_CLASS_SYLVESTRE_2005_PLUS_CANADIAN_ONLY_DISTILLATION_TY_EXPLICIT_PLUS_LIMITED_AVAILABILITY_TY_EXPLICIT_PLUS_PRECAUTIONARY_PREGNANCY_REDUCED_CAP_DUE_TO_DATA_GAP_PLUS_INSECT_REPELLENT_REPUTATION_TY_EXPLICIT_PLUS_MYRICACEAE_FAMILY_SINGLETON_NOT_MYRTACEAE_DESPITE_COMMON_NAME_BOG_MYRTLE_VS_TRUE_MYRTLE_NOMENCLATURAL_COLLISION_RAIL
oxidation_risk
medium
max_dilution_2_6
2.5
drug_interactions
[]
max_dilution_6_12
3
shelf_life_months
24
max_dilution_adult
5
contraindicated_all
false
max_dilution_elderly
2.5
max_oral_dose_mg_day
200
max_dilution_sensitive
2.5
max_dilution_adult_face
2.5
contraindicated_children
false
contraindicated_pregnancy
false
max_dilution_child_under2
1
max_dilution_breastfeeding
2.5
max_dilution_pregnancy_1st
2.5
max_dilution_pregnancy_2nd
2.5
max_dilution_pregnancy_3rd
2.5
max_oral_dose_mg_day_pregnancy
0

Luận Giải Văn Cảnh

hazards

hazards: [hazards_none_known_TY_EXPLICIT_VERBATIM_p711, contraindications_none_known_TY_EXPLICIT_VERBATIM_p711, no_information_found_adverse_skin_reactions_data_gap_TY_EXPLICIT_p712, no_information_found_acute_toxicity_data_gap_TY_EXPLICIT_p712, anticarcinogenic_class_documented_sylvestre_2005_phytomedicine_a549_lung_carcinoma_colon_adenocarcinoma, beta_caryophyllene_11_pct_MAJOR_DOMINANT_anticarcinogenic_class, beta_myrcene_9_5_pct_secondary_latent_oxidation_precaution_class, limonene_7_2_pct_tertiary_IFRA_peroxide_control_anticarcinogenic_class, sesquiterpene_class_35_pct_combined, monoterpene_class_27_pct_combined_latent_autoxidation_precaution, alpha_cadinol_anticarcinogenic_he_1997a, germacrone_anticarcinogenic_zhong_2011, canadian_only_commercial_distillation_TY_EXPLICIT_p712, limited_availability_commercial_niche_TY_EXPLICIT_p712, insect_repellent_reputation_TY_EXPLICIT_p712, myricaceae_family_NOT_myrtaceae_apg_iv_taxonomic_correction_b216_typo_p711, distillation_time_chemotype_variance_sylvestre_2005_30min_vs_60min, no_thujone_no_camphor_no_pulegone_no_methyleugenol_clean_class]

storage

oxidation_risk: medium

dilution

max_dilution_adult: 5

botanical

latin_name: Myrica gale L

chemistry

dominant_constituent: β-Caryophyllene

commercial

availability: limited

oil_metadata

slug: myrtle-bog

safety_flags

phototoxic: FALSE

Tài Liệu Y Khoa Tham Khảo

  • B216 (Tisserand & Young 2014, "Essential Oil Safety, 2nd Ed.") — Ch.13 p.711 Myrtle (bog) profile (primary source)
  • Mainguy 2001 (private communication)Myrica gale essential oil chemistry profile (cited in B216 Ch.13 p.711)
  • Sylvestre et al 2005 — Phytomedicine 12:299–304 Canadian bog myrtle oil anticarcinogenic chemistry vs A-549 + colon adenocarcinoma + distillation-time variance
  • He et al 1997a — α-cadinol active human colon cancer cells
  • Zhong et al 2011 — germacrone active human breast cancer cells
  • B216 β-Caryophyllene profile Chapter 14 — anticarcinogenic-class profile
  • B216 β-Myrcene profile Chapter 14 — latent-autoxidation precaution-class
  • B216 (+)-Limonene profile Chapter 14 — IFRA peroxide-control + anticarcinogenic-class
  • APG-IV (2016) — Myricaceae family taxonomic placement modern molecular phylogenetics