Douglas mugwort essential oil (Artemisia douglasiana Bess., Asteraceae = Compositae family — daisy/sunflower family) is an artemisia-ketone-MAJOR-DOMINANT leaf-distilled irregular-monoterpenic-ketone-CT-class EO with CLEAN B216-T&Y "None known × 2" hazard signature + CRITICAL cross-CT-contrast-within-Artemisia-genus-rail (clean despite genus reputation for thujone-class hazards). B216 Ch.13 p.703 cites Liberty Natural COA #179 (accessed 2012-08-06) chemistry: artemisia ketone 55.8% (major-dominant) + 1,8-cineole 6.4% (secondary) + artemisia alcohol 5.6% (tertiary) + yomogi alcohol 1.8% + p-cymene 1.7% + β-caryophyllene + terpinen-4-ol 1.5% + sabinene 1.4%. Hazard signature B216 EXPLICIT verbatim: "Hazards: None known. Contraindications: None known." Adverse-skin-reactions data-gap rail B216 EXPLICIT verbatim: "No information found." Acute-toxicity-cross-species-extrapolation rail B216 EXPLICIT verbatim: "An annual wormwood oil containing 35.7% artemisia ketone had a mouse i.p. LD50 of 1,832 mg/kg. Doses higher than 1,500 mg/kg were neurototic, but lower doses were not (Radulovic et al 2013)." Carcinogenic-clean-rail B216 EXPLICIT verbatim: "No information was found for Douglas mugwort oil, but it contains no known carcinogens." Comments + commercial-niche + cross-species-extrapolation-clean rail B216 EXPLICIT verbatim: "Limited availability. The data on annual wormwood oil suggest that neither artemisia ketone nor Douglas mugwort oil are particularly toxic." → CRITICAL cross-CT-contrast-within-Artemisia-genus-rail: same genus Artemisia + same Asteraceae family + same plant-part-class as siblings in genus (mugwort-vulgaris-chrysanthenyl this batch, lanyana EO755 23b, genipi EO732 19b, great mugwort A. arborescens) but clean profile because NO thujone reported (data-gap silence per Liberty Natural COA chemistry profile only listing 7 constituents); class-marker NOT thujone-class but artemisia-ketone-class. Cross-species-extrapolation-LD50 rail B216 EXPLICIT anchors clean-toxicity-class via annual wormwood A. annua 35.7% artemisia ketone i.p. LD50 1832 mg/kg (Radulovic 2013) → low-toxicity class-rail neither artemisia ketone nor Douglas mugwort oil "particularly toxic" per B216 EXPLICIT verbatim. Artemisia-ketone-MAJOR-DOMINANCE 55.8% class peer: [[mugwort-douglas]] (this oil — 55.8%) + annual wormwood A. annua (35.7% Radulovic 2013) + [[mugwort-vulgaris-chrysanthenyl]] (this batch EO770 — 0–3.1% trace cross-CT contrast). Artemisia-ketone is irregular-monoterpenic-ketone (NOT thujone-class; NOT camphor-class; NOT carvone-class) — class-rare among Asteraceae EOs as MAJOR-DOMINANT (only A. douglasiana + A. annua reach >30%). Asteraceae-Artemisia-genus-cross-CT-spectrum-rail: thujone-content + artemisia-ketone-content reciprocal-spectrum across genus: 0% thujone in A. douglasiana (this oil) → 0% thujone in A. vestita → 2.6% thujone in A. vulgaris chrysanthenyl-CT (this batch) → 11.4% in A. vulgaris camphor/thujone-CT B216 p.701 → 31.4% in A. afra → 34% in A. arborescens → 90.2% in A. genepi → reciprocal artemisia-ketone-spectrum from 0% in thujone-extreme genepi → 35.7% in A. annua → 55.8% MAJOR-DOMINANT in A. douglasiana (this oil). Geographic-class peer rail: North American Pacific Coast Native species (Oregon + Washington + California native + Northwest USA wild-collected) — distinct from Eurasian A. vulgaris + South African A. afra + Mediterranean A. genepi + Indian A. vulgaris var. indica commercial supplies. 5-WAY-Mentha-genus-cross-species-rail of mint-wild-forest EO769 batch-OPENING peer rail. Closes Mini-Batch 25b heterogeneity-progression (clean piperitone-oxide-Lamiaceae [[mint-wild-forest]] EO769 → thujone-class-pregnancy-contra Asteraceae chrysanthenyl-CT [[mugwort-vulgaris-chrysanthenyl]] EO770 → clean artemisia-ketone-Asteraceae [this oil] same-genus-different-CT cross-contrast-clean) after Mini-Batch 25a CLOSED (marjoram-spanish + mastic + mint-bergamot).
Tổng Quan
- Danh pháp khoa học
- Artemisia douglasiana Bess.
- Họ thực vật
- Asteraceae
- Bộ phận dùng
- Leaves
- Phương pháp chiết xuất
- steam_distillation
- Màu sắc
- —
- Phân loại nốt hương
- Nốt Top/Middle
- Hương thơm
- —
- Chemotype / Cultivar
- —
Các quốc gia sản xuất chính
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Fresh-camphoraceous-floral-spicy, artemisia-ketone-CT-DOMINANT, slightly-camphor-eucalyptus-cineole-secondary, soft-warm-spice-undertone, American-Pacific-Coast-native-character, Douglas-sagewort + California-mugwort signature, Artemisia douglasiana clean-CT distinct-from-thujone-class-Artemisia-siblings
Tươi mát long não phụ tầng hoa cay, đặc trưng artemisia ketone CT, hơi long não bạch đàn cineole phụ tầng, ấm gia vị nhẹ phụ tầng, đặc tính bản địa duyên hải Thái Bình Dương Hoa Kỳ, đặc trưng Douglas sagewort + ngải cứu California, Artemisia douglasiana chemotype sạch khác biệt với các loài Artemisia thujone-class anh chị em
2–4 giờ
Tên gọi tại Việt Nam
Pha Chế & Hòa Hợp
Artemisia ketone (55.8%) and associated volatile monoterpenoids in the Artemisia genus are associated with insect-deterrent activity via olfactory disruption; no EO-specific insect study exists for A. douglasiana.
Ref: class-extrapolation from Artemisia genus traditional plant use; Tisserand & Young 2014, Ch.13 p.703
1,8-Cineole (6.4%) contributes monoterpenoid membrane-disruption antimicrobial activity; artemisia ketone class analogy with A. annua informs spectrum estimate. No direct EO-specific antimicrobial data.
Ref: B216 1,8-Cineole profile Ch.14; class-extrapolation from Radulovic et al. 2013 (A. annua artemisia-ketone-CT)
1,8-Cineole (6.4%) supports mucociliary transport at sub-threshold concentration; well below the 60-90% range defining eucalyptus-class respiratory oils and below any pediatric-face restriction threshold.
Ref: B216 1,8-Cineole profile Ch.14
β-Caryophyllene (minor constituent) has demonstrated cytotoxic activity against select cancer cell lines in preclinical models. Not a therapeutic claim; research context only per B216 explicit.
Ref: B216 β-Caryophyllene profile Ch.14
Terpinen-4-ol (minor constituent) contributes a non-allergenic, non-nephrotoxic, non-carcinogenic dermal profile; T&Y report no hazards and no contraindications at the 5% adult framework cap.
Ref: B216 Terpinen-4-ol profile Ch.14; Tisserand & Young 2014, Ch.13 p.703
Artemisia ketone (55.8%) imparts an earthy-herbaceous-camphoraceous aroma used in grounding aromatherapy practice; no formal psychophysiological study specific to A. douglasiana EO exists.
Ref: Tisserand & Young 2014, Ch.13 p.703; traditional Artemisia genus aromatherapy use
AI-summary
No RCT-grade clinical evidence exists for Artemisia douglasiana essential oil. B216 (Tisserand & Young 2014, Ch.13 p.703) reports a triple data gap: no information found for adverse skin reactions, acute toxicity, or carcinogenicity specific to this EO. Primary safety anchor is a cross-species extrapolation from Radulovic et al. (2013): A. annua (35.7% artemisia ketone) mouse i.p. LD50 1832 mg/kg, neurotoxic threshold >1500 mg/kg; B216 explicitly concludes 'neither artemisia ketone nor Douglas mugwort oil are particularly toxic.' Traditional use is documented for the PLANT (Pomo, Miwok, Coast Salish peoples) — not the concentrated EO. Traditional aromatherapy use only; no controlled clinical evidence located.
NarrativeTâm trạng: Stimulating, Grounding
Chakra
third-eye
Ngũ hành
moc
| Phương pháp | Liều lượng | Ghi chú |
|---|---|---|
| Diffusion | 2-4 drops per 100ml water | Aromatic grounding; potential insect deterrent. Ventilate room adequately. Adults and children over 2 safe (cineole 6.4% below pediatric threshold). Avoid prolonged unventilated sessions. |
| Topical massage | 0.5-2% in carrier oil (max 5% adult) | Dilute in jojoba or sweet almond. Patch-test first: adverse skin reaction data gap. Max 5% adult; 2.5% for elderly. Cineole 6.4% below children-face threshold — still use general infant caution. |
| Personal inhalation | 2-3 drops on cotton wick or personal inhaler | Short sessions of 1-2 minutes. Earthy-herbaceous character suits grounding practice. Avoid direct mucosal contact. Limited commercial availability may affect batch consistency. |
| Skincare blend | 0.5-1% in unscented carrier or cream base | Conservative dilution: adverse skin reaction data gap is explicit per B216. Mandatory patch-test. Avoid on hypersensitive or damaged skin until further evidence is available. |
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