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Tinh dầu nhũ hương mastic

Mastic

Pistacia lentiscus L.

Top/MiddleGỗ

Nhựa thông long não cổ điển mastic, α-pinene tươi mát đặc trưng, hơi ngọt nhựa thơm balsamic ấm, thảo mộc β-myrcene phụ tầng, hương nhựa Địa Trung Hải, đặc tính Chios-mastiha, signature mastic Hy Lạp cổ điển

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Tóm Tắt Khoa Học

Từ Thư Viện Kinh Điển

Mastic essential oil (Pistacia lentiscus L., Anacardiaceae = cashew family — same family as cashew/pistachio/sumac/poison-ivy) is an α-pinene-EXTREME-DOMINANCE 58.8–78.6% gum-resin-distilled monoterpene-hydrocarbon-class EO with T&Y EXPLICIT 20% adult dermal cap methyleugenol-carcinogen-DERIVED + MANDATORY refrigerated storage + MANDATORY antioxidant-at-production hazard signature. B216 Ch.13 p.694–695 cites Lawrence 1995g + Magiatis et al 1999 chemistry: α-pinene 58.8–78.6% (extreme-dominant) + β-myrcene 0.2–12.3% (variable secondary) + linalool 0.1–3.7% + β-pinene 1.2–3.3% + verbenone 0–2.9% + pinocarveol tr–2.1% + β-caryophyllene 0.2–2.0% + (+)-limonene 0.4–1.6% + methyl-o-cresol 0.4–1.2% + camphoraldehyde II tr–1.1% + caryophyllene oxide tr–1.1% + methyleugenol tr–0.1%. Hazard signature B216 EXPLICIT verbatim: "Hazards: May contain methyleugenol. Contraindications: None known." CRITICAL T&Y EXPLICIT cap-derivation rail B216 verbatim: "We recommend a dermal maximum of 20%, based on 0.1% methyleugenol content with a dermal limit of 0.02% (see Methyleugenol profile, Chapter 14)." → Adult dermal cap 20% (T&Y EXPLICIT) is methyleugenol-carcinogen-CAP-DERIVED, NOT framework. Compare to EU 0.2% + IFRA 0.4% (much more conservative regulatory). CRITICAL T&Y EXPLICIT mandatory-storage-rail B216 verbatim: "Because of its high α-pinene content we recommend that oxidation of mastic oil is avoided by storage in a dark, airtight container in a refrigerator. The addition of an antioxidant to preparations containing it is recommended." → MANDATORY refrigerated storage + MANDATORY antioxidant-at-production class-rail with [[longoza]] EO761 24a (β-pinene+α-pinene 48–76%), [[kanuka]] EO749 22b (α-pinene 55.5%), [[larch-needle]] EO756 23b (α-pinene 38.5%), [[fir-douglas]] EO719 17c, all Pinaceae conifer-needle EOs. Adverse-skin-reactions class-rail B216 EXPLICIT: "No information was found for the essential oil, but autoxidation products of α-pinene can cause skin sensitization." → α-pinene-autoxidation-sensitization class-rail mandatory peroxide-control. Regulatory-rail B216 EXPLICIT IFRA 2009 + SCCNFP 2002: IFRA 0.0004% methyleugenol leave-on body-lotion + SCCNFP 0.0002% — much more conservative than T&Y. Reproductive-toxicity LOW class-rail B216 EXPLICIT: low repro tox of α-pinene + β-myrcene + linalool → NOT hazardous in pregnancy. Acute-toxicity α-pinene-class-rail B216 EXPLICIT Opdyke 1978 p.853–857: α-pinene LD50 rats 2.1, 3.2, 3.7 g/kg; rabbits < 5 g/kg (no EO-direct data). Anticarcinogenic-class-rail B216 EXPLICIT: P. lentiscus var. chia oil inhibited proliferation + angiogenesis of K562 human leukemia cells (Loutrari et al 2006); class-rail-only marker NOT therapeutic claim. (+)-Limonene anticarcinogenic class. Methyleugenol carcinogen-class-rail B216 EXPLICIT: rodent carcinogen if exposure sufficiently high (Ch.14). α-Pinene EXTREME-DOMINANCE 58.8–78.6% class peer: [[longoza]] EO761 24a (48–76% β+α-pinene combined) + [[kanuka]] EO749 22b (55.5%) + [[larch-needle]] EO756 23b (38.5%) + [[fir-douglas]] EO719 17c + [[fir-cones-silver]] EO720 17c + fir-needle Canadian/Himalayan/Japanese/Siberian/Silver EO721–725 + [[hemp]] EO739 21a (β-myrcene 21–31% but α-pinene minor; latent-oxidation-only class) + [[hibawood]] EO740 21a + many Pinaceae + Cupressaceae + Lamiaceae α-pinene-rich EOs. Anacardiaceae-family-singleton-rail (FIRST in batch sequence): mastic is the FIRST Anacardiaceae EO in the wiki — class-shared with cashew Anacardium occidentale + pistachio Pistacia vera (same genus Pistacia) + sumac Rhus + poison-ivy Toxicodendron + mango Mangifera; Anacardiaceae family-class characterized by alkenyl-phenol allergens (urushiol-class) but EO-specific gum-resin-distillation strips these → mastic EO clean of urushiol. Continues Mini-Batch 25a heterogeneity-progression between [[marjoram-spanish]] EO766 25a (Lamiaceae cineole-major-dominance children-face-contra) and [[mint-bergamot]] EO768 25a (Lamiaceae Mentha aquatica linalyl-acetate-linalool-DOMINANT clean cross-species).

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Thận trọngNốt Top/MiddleResinous-piney-balsamic-Mediterranean-mastic-gum + slightly-sweet-woody + classical-Greek-ma...

Mastic

Tinh dầu nhũ hương mastic

Pistacia lentiscus L.

Tinh dầu nhũ hương mastic — Resinous-piney-balsamic-Mediterranean-mastic-gum + slightly-sweet-woody + classical-Greek-ma...

⚠️Tinh dầu này cần thận trọng khi sử dụng. Đọc kỹ hướng dẫn an toàn.

Tổng Quan

Danh pháp khoa học
Pistacia lentiscus L.
Họ thực vật
Anacardiaceae
Bộ phận dùng
Gum resin
Phương pháp chiết xuất
steam_distillation
Màu sắc
Phân loại nốt hương
Nốt Top/Middle
Hương thơm
Chemotype / Cultivar

Các quốc gia sản xuất chính

GreeceTurkeyMorocco

Tình trạng tại Việt Nam

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Phân loại nốt
Top-Middle
Cường độ
4/5
Độ bền trên da
2–4 giờ
Họ hương
Resinous-piney-balsamic-Mediterranean-mastic-gum + slightly-sweet-woody + classical-Greek-ma...
Hương đầu (Opening)(0–15 phút)

Resinous-piney-balsamic-classical-mastic, fresh-α-pinene-DOMINANT, slightly-sweet-balsamic-warm-undertone, herbaceous-β-myrcene-secondary, Mediterranean-aromatic-resin, Chios-mastiha-character, classical-Greek-mastic-signature

Hương giữa (Heart)(15–60 phút)

Nhựa thông long não cổ điển mastic, α-pinene tươi mát đặc trưng, hơi ngọt nhựa thơm balsamic ấm, thảo mộc β-myrcene phụ tầng, hương nhựa Địa Trung Hải, đặc tính Chios-mastiha, signature mastic Hy Lạp cổ điển

Hương nền (Drydown)(1–4 giờ)

2–4 giờ

Cường độ hương
4/5
Da khô
2/5

Da dầu/mụn
4/5

Da lão hóa
3/5

Da thường
3/5

Da nhạy cảm
2/5

Da hỗn hợp
4/5

Nhập khẩuImported

Tên gọi tại Việt Nam

Tinh dầu nhũ hương mastic

Pha Chế & Hòa Hợp

antimicrobial — broad-spectrum

α-Pinene (58.8–78.6%) disrupts bacterial cell membrane integrity via monoterpene-hydrocarbon class mechanism; class-extrapolated from constituent-level evidence.

Ref: class-extrapolation from B216 α-Pinene profile Chapter 14; Tisserand & Young 2014, Ch.13 p.694

anti-inflammatory

α-Pinene inhibits NF-κB-mediated prostaglandin synthesis and 5-lipoxygenase pathways; mechanistic class-extrapolation from α-pinene constituent-level evidence.

Ref: class-extrapolation from B216 α-Pinene profile Chapter 14

expectorant — upper respiratory

α-Pinene stimulates mucociliary clearance and acts as a mild bronchodilator, thinning bronchial secretions to support airway patency; class-extrapolated from α-pinene constituent data.

Ref: class-extrapolation from B216 α-Pinene profile Chapter 14

anticarcinogenic — in vitro only

Pistacia lentiscus var. chia EO inhibited proliferation and angiogenesis of K562 human leukemia cells in vitro; molecular mechanism not elucidated; B216 explicitly states this is NOT a therapeutic claim.

Ref: Loutrari et al 2006, cited in Tisserand & Young 2014, Ch.13 p.694

topical antiseptic

Monoterpene-dominant profile (α-pinene extreme-dominance) confers surface antimicrobial activity consistent with 2,500-year Chios PDO mastiha topical healing tradition.

Ref: Tisserand & Young 2014, Ch.13 p.694; traditional Chios PDO mastiha heritage

AI-summary

The sole controlled study available for Pistacia lentiscus EO is an in vitro experiment: Loutrari et al (2006) demonstrated that P. lentiscus var. chia essential oil inhibited proliferation and angiogenesis of K562 human leukemia cells in culture. Tisserand & Young (2014, Ch.13 p.694) cite this result as an anticarcinogenic research signal while explicitly noting it does NOT constitute a therapeutic claim. No clinical RCTs evaluating mastic EO for any human therapeutic endpoint have been located in the available evidence base. Remaining therapeutic attributions (antimicrobial, anti-inflammatory, expectorant) are mechanistic class-extrapolations from the dominant constituent α-pinene (58.8–78.6%), supported by B216 Chapter 14 constituent-level data, not direct oil-level clinical evidence. The 2,500-year Chios PDO mastiha tradition supports traditional-use plausibility but does not substitute for controlled clinical evaluation.

Narrative

Tâm trạng: Uplifting, Grounding

clarityfocusgroundingvitalityinner peaceancient wisdom

Chakra

third-eye

Ngũ hành

kim

Phương phápLiều lượngGhi chú
Diffusion3–5 drops in 100 ml water (ultrasonic) or 3 drops (nebulizer)Supports respiratory clarity and ambient antimicrobial effect. Use only fresh, refrigerated-stored oil. Avoid near infants under 6 months.
Topical massage — aromatherapy1–5% in carrier; T&Y adult cap 20%; EU/IFRA cosmetic max 0.2–0.4%Use only refrigerated, antioxidant-stabilized oil. Perform patch test — sensitization risk with oxidized oil. Pregnancy: standard framework safe per T&Y.
Steam inhalation2–3 drops in bowl of hot water; inhale 5–10 min with eyes closedSupports upper respiratory mucus clearance. Maintain safe distance from bowl. Suitable for adults; limit to brief exposure for children 6+.
Skincare blend — EU/IFRA compliant0.5–1% in stable carrier; max 0.4% in EU/IFRA-regulated leave-onBest for oily/combination skin. MANDATORY: use fresh oil with antioxidant at production, refrigerator-stored. Do not use oxidized oil on face.
Warm compress3–4 drops in 500 ml warm water; wring cloth, apply to affected areaFor localized anti-inflammatory support. Use warm not hot water. Avoid broken or sensitized skin. Change compress when cooled.

Dầu nền phù hợp

Jojoba (liquid wax)Extremely stable ester composition resists rancidity, complementing mastic's mandatory antioxidant-stabilized storage protocol; non-comedogenic; suited for oily/combination skin.
Fractionated coconut oilHighly stable saturated MCT profile minimizes oxidative load; light texture suits respiratory blends and topical antiseptic applications; long shelf life.
Sweet almond oilTraditional Mediterranean carrier aligning with Chios PDO mastiha heritage; medium-weight, good spreadability for body and face massage blends.
Argan oilHigh oleic acid stability, Mediterranean heritage alignment; suits mature and normal skin; antioxidant tocopherol content may partly offset α-pinene autoxidation risk.

Kết hợp tốt với

WoodyHerbaceousCitrusCamphoraceous

Blend kinh điển

[B216] Ch.13 p.694 Mastic profile (this is primary source)
[Lawrence 1995g p.19, p.69] Pistacia lentiscus essential oil chemistry (cited in B216 Ch.13 p.694)
[Magiatis et al 1999] Mastic essential oil chemistry (cited in B216 Ch.13 p.694)
[Opdyke 1978 p.853–857] α-pinene acute oral LD50 rats 2.1, 3.2, 3.7 g/kg + acute dermal LD50 rabbits < 5 g/kg (cited in B216 Ch.13 p.694)
[Loutrari, H., Magkouta, S., Pyriochou, A., et al 2006] Pistacia lentiscus var. chia oil inhibited proliferation + angiogenesis of human leukemia K562 cells (cited in B216 Ch.13 p.694)
[B216 α-Pinene profile Chapter 14] autoxidation skin sensitization class-rail + low reproductive toxicity + acute toxicity LD50 data
[B216 Methyleugenol profile Chapter 14] rodent carcinogen + dermal limit 0.02% basis for T&Y 20% mastic cap derivation
[B216 β-Myrcene profile Chapter 14] low reproductive toxicity class-rail
[B216 Linalool profile Chapter 14] low reproductive toxicity + IFRA 2009 peroxide-control class-rail
[IFRA 2009] methyleugenol max 0.0004% leave-on body-lotion regulatory
[SCCNFP / European Commission 2002] methyleugenol max 0.0002% regulatory

An Toàn

Giới hạn da tối đa

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Giới hạn IFRA

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Thai kỳ & Cho con bú

Tam cá nguyệt 1Unknown
Tam cá nguyệt 2Unknown
Tam cá nguyệt 3Unknown

Giới hạn độ tuổi

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Bảo quản

Bảo quản nơi tối, mát

Thông tin chỉ mang tính tham khảo, không thay thế tư vấn y tế chuyên nghiệp. SYMELab v2.0

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Hồ Sơ Hoá Học Chi Tiết
§3 Chemical Profile — chemotype, constituent ranges, adulteration

Per Lawrence 1995g p.19, p.69 + Magiatis et al 1999 cited in B216 Ch.13 p.694:

Constituent%Role
α-Pinene58.8–78.6%Extreme-dominant — bicyclic monoterpene; fresh-piney-resinous-balsamic; class-shared with [[longoza]] EO761 24a (48–76% β+α combined) + [[kanuka]] EO749 22b (55.5%) + [[larch-needle]] EO756 23b (38.5%) + [[fir-douglas]] EO719 17c + [[fir-cones-silver]] EO720 17c + Pinaceae conifer-needle EOs + [[hibawood]] EO740 21a + [[hinoki-leaf]] EO741 21a + many Cupressaceae + Lamiaceae α-pinene-rich; α-pinene-EXTREME-DOMINANCE class-rail MANDATORY refrigerated storage + antioxidant-at-production B216 EXPLICIT
β-Myrcene0.2–12.3%Variable secondary — acyclic monoterpene; herbaceous-warm-resinous; class-shared with [[hemp]] EO739 21a (21–31% French/Swiss chemotypes) + [[grindelia]] EO736 20b (14–26%); broad range 0.2–12.3% indicates significant chemotype-variation between commercial sources
Linalool0.1–3.7%Acyclic monoterpenic alcohol — floral-fresh-sweet; minor cap-driver class-rail with [[linaloe-wood]] EO760 24a + lavender + many linalool-CT EOs; latent-oxidation IFRA 2009 peroxide-control class-rail (low pct so minimal)
β-Pinene1.2–3.3%Bicyclic monoterpene — fresh-piney-cooler-undertone; class-rail with [[marjoram-spanish]] EO766 25a (this batch — 2.3–5.1%) + α-pinene-rich conifer EOs
Verbenone0–2.9%Bicyclic ketone monoterpene — minty-fresh-resinous; class-rail with rosemary-verbenone-CT (Corsican chemotype)
Pinocarveoltr–2.1%Bicyclic alcohol monoterpene — fresh-piney-camphoraceous-undertone; α-pinene-oxidation-derivative class-rail
β-Caryophyllene0.2–2.0%Bicyclic sesquiterpene — woody-spicy-warm-undertone; CB2-receptor binding class-rail; class-shared with most aromatic plants
(+)-Limonene0.4–1.6%Cyclic monoterpene — fresh-citrus; latent-oxidation class-rail with [[lemon-balm]] EO759 23c + many citrus EOs; B216 EXPLICIT anticarcinogenic-activity class-rail (low pct so minimal cap-driver here but class-marker)
Methyl-o-cresol0.4–1.2%Aromatic methyl-cresol — phenolic-medicinal-undertone; minor cap-driver
Camphoraldehyde IItr–1.1%Bicyclic aldehyde — camphor-derivative; trace
Caryophyllene oxidetr–1.1%Sesquiterpene-oxide — woody-spicy-oxidized-undertone; trace
Methyleugenoltr–0.1%Phenolpropanoid carcinogen-class — T&Y EXPLICIT cap-driver "We recommend a dermal maximum of 20%, based on 0.1% methyleugenol content with a dermal limit of 0.02% (see Methyleugenol profile, Chapter 14)"; rodent carcinogen if exposure sufficiently high; IFRA 2009 max 0.0004% leave-on body-lotion + SCCNFP 2002 max 0.0002%; class-shared with [[laurel-berry]] EO757 23c (1.0%) + [[hyacinth]] EO745 22a (carcinogen-cap-driver) + champaca-orange EO703 16a + champaca-white EO704 16a (split chemistry) + many methyleugenol-trace EOs

α-Pinene EXTREME-DOMINANCE 58.8–78.6% rail: Single-constituent extreme-dominance class-shared with longoza/kanuka/larch-needle/fir-douglas/fir-cones-silver/Pinaceae conifer-needle cluster. Mastic is the α-pinene-EXTREME-DOMINANCE-Anacardiaceae-gum-resin class — distinct from longoza (Zingiberaceae rhizomes β+α-pinene) and kanuka (Myrtaceae leaves α-pinene) and larch-needle (Pinaceae needles α-pinene). Cross-family α-pinene-extreme-dominance class-rail mandates same MANDATORY refrigerated storage + antioxidant-at-production protocol regardless of family.

α-Pinene-autoxidation-skin-sensitization class-rail B216 EXPLICIT verbatim ("autoxidation products of α-pinene can cause skin sensitization") + IFRA 2009 Pinaceae class-wide regulatory peroxide-control: any α-pinene-rich EO (≥30% α-pinene) MUST be stored refrigerated dark airtight + manufacturer adds antioxidant (BHT 0.1% or α-tocopherol 0.1%) at production to prevent peroxide formation that drives skin sensitization.

Methyleugenol carcinogen-class T&Y-EXPLICIT-cap-derivation rail: T&Y derived adult dermal max 20% based on:

  • Methyleugenol max in mastic EO = 0.1% (top of 0–0.1% range)
  • T&Y dermal limit for methyleugenol = 0.02% in final product (Ch.14 Methyleugenol profile)
  • Calculation: 0.02% ÷ 0.1% = 20% mastic EO max in product
  • → 20% adult dermal cap is methyleugenol-carcinogen-CAP-DERIVED, NOT framework (compare: framework 5% for clean-T&Y "None known × 2" oils; mastic gets 4× higher cap because methyleugenol is the only safety driver and clinical/animal data shows mastic itself is well-tolerated)
  • Regulatory-conservatism rail: EU + IFRA much more conservative (0.0004% methyleugenol leave-on); class-rail tension between T&Y safety calculation vs regulatory market-restriction approaches

No-EO-direct-acute-toxicity-data + α-pinene-class-LD50-2.1-3.7-g-per-kg rail B216 EXPLICIT (Opdyke 1978 p.853–857): no EO direct data; α-pinene LD50 rats 2.1, 3.2, 3.7 g/kg; rabbits < 5 g/kg → class-rail mastic EO acute-tox profile via α-pinene-extreme-dominance.

Anticarcinogenic-class-rail B216 EXPLICIT (Loutrari et al 2006): P. lentiscus var. chia oil inhibited proliferation + angiogenesis of human leukemia K562 cells; (+)-limonene displays anticarcinogenic activity (Ch.14); class-rail-only marker NOT therapeutic claim — cell-culture cytotoxicity ≠ clinical anticancer therapeutic use.

Low-reproductive-toxicity-class-rail B216 EXPLICIT verbatim ("The low reproductive toxicity of α-pinene, β-myrcene and linalool suggests that mastic oil is not hazardous in pregnancy.") → NOT hazardous in pregnancy via 3-constituent class-rail.

Công Dụng Trị Liệu Chi Tiết
§10 Therapeutic Uses — skin, emotional, physical, respiratory

Per B216 + Mediterranean traditional + modern aromatherapy:

  • Antimicrobial / anti-H.pylori (Loutrari + clinical literature on mastic gum H.pylori inhibition; class-rail with α-pinene-rich antimicrobial EOs)
  • Anti-inflammatory (theoretical from α-pinene + β-caryophyllene class)
  • Anticarcinogenic-class-rail (Loutrari 2006 K562 leukemia + (+)-limonene class — class-rail-only marker NOT therapeutic claim)
  • Digestive support (traditional Greek + Mediterranean mastic-resin-tea + chewing-resin class)
  • Dental / oral hygiene (mastic chewing-gum traditional + modern oral-care formulation; class-rail with α-pinene + methyleugenol antimicrobial)
  • Wound healing (traditional Mediterranean mastic-resin-poultice class)
  • Classical perfumery (resinous-balsamic accent in Levantine + Middle-Eastern + classical-Greek attar tradition)
  • Functional fragrance (mass-market gum/dental/cosmetic mastic-resin-flavor class-rail)
  • Vietnamese aromatherapy context: Tinh dầu nhũ hương mastic (Pistacia lentiscus — họ điều Anacardiaceae, HỌ KHÁC HOÀN TOÀN với các họ Lamiaceae / Myrtaceae / Pinaceae của các tinh dầu α-pinene-extreme-dominance khác — gum-resin-distillation đặc trưng) là tinh dầu α-pinene 58.8–78.6% extreme-dominance + β-myrcene 0.2–12.3% biến thiên + linalool 0.1–3.7% + β-pinene 1.2–3.3% combined ~70–95% chiết xuất từ nhựa thơm gum. Hồ sơ an toàn ĐẶC BIỆT: T&Y CẤM cụ thể ngưỡng 20% người lớn (cao hơn framework 4 lần) — derivation methyleugenol-cap (0.1% methyleugenol × 20% = 0.02% T&Y dermal limit Methyleugenol Ch.14); CHỐNG CHỈ ĐỊNH KHÔNG có (B216 EXPLICIT "None known"); BẮT BUỘC bảo quản TỦ LẠNH + thêm chất chống oxy hóa lúc sản xuất (B216 EXPLICIT cảnh báo α-pinene autoxidation gây nhạy cảm da); độc sinh sản THẤP (α-pinene+β-myrcene+linalool class) → KHÔNG nguy hiểm thai kỳ, không gây ung thư trực tiếp (methyleugenol class-rail rodent-carcinogen ở liều cao). Quy định EU 0.2% + IFRA 0.4% NGẶT hơn nhiều so với T&Y 20%. Hương đặc trưng nhựa thơm cổ điển Mediterranean-mastic-gum (α-pinene-extreme-dominance class peer longoza + kanuka + larch-needle + Pinaceae conifer cluster). Class-rail Anacardiaceae-family-FIRST-singleton trong wiki (mastic là EO Anacardiaceae đầu tiên ingest; cảnh báo họ điều có urushiol-allergen-class trong nhựa tươi nhưng STEAM DISTILLATION đã loại bỏ → mastic EO sạch urushiol). Heritage Chios-mastiha PDO Greek truyền thống ngàn năm (kẹo cao su mastic + bánh kẹo Hy Lạp + dược cổ truyền + nha khoa).
Năng Lượng & Ngũ Hành
§11 Energetics — TCM, Ayurveda, aromatic energetics
  • Five Element: Metal (resinous-Anacardiaceae-class); Earth (digestive-supportive traditional)
  • Chakra: Solar plexus (3rd) — digestive-traditional; Throat (5th) — respiratory-α-pinene-class
  • Ayurvedic: Vata-warming via α-pinene; Kapha-clearing via resinous; Pitta-neutral
  • TCM: Warming + qi-moving + lung-meridian-supporting via α-pinene-class
  • Mood: Grounding + clarifying + warming per modern aromatherapy + classical resinous-balsamic perfumery context
  • Heritage: Chios island Greek PDO-protected mastiha 2,500-year heritage (Mediterranean confectionery + dental + traditional medicine); ancient classical Greek + Roman + Byzantine + Ottoman + modern Greek economy; classical perfumery resinous-balsamic Levantine + Middle-Eastern attar tradition; modern aromatherapy niche

Dữ Liệu Kỹ Thuật Y Khoa

§14 Renderer Contract — Tisserand & Young V2.2

Thông Số Định Lượng

hazards
["TY_EXPLICIT_HAZARDS_MAY_CONTAIN_METHYLEUGENOL_p694","TY_EXPLICIT_CONTRAINDICATIONS_NONE_KNOWN_p694","TY_EXPLICIT_DERMAL_MAX_20pct_methyleugenol_carcinogen_cap_derived_0_1pct_methyleugenol_x_20pct_equals_0_02pct_methyleugenol_in_product_TY_dermal_limit_methyleugenol_chapter_14","TY_EXPLICIT_MANDATORY_REFRIGERATED_STORAGE_high_alpha_pinene_content_oxidation_avoided_by_storage_dark_airtight_refrigerator","TY_EXPLICIT_MANDATORY_ANTIOXIDANT_AT_PRODUCTION_BHT_or_alpha_tocopherol_addition_recommended","TY_EXPLICIT_alpha_pinene_autoxidation_can_cause_skin_sensitization_class_rail_chapter_14","TY_EXPLICIT_low_reproductive_toxicity_alpha_pinene_AND_beta_myrcene_AND_linalool_NOT_hazardous_in_pregnancy","TY_EXPLICIT_no_EO_direct_acute_toxicity_data_alpha_pinene_LD50_rats_2_1_3_2_3_7_g_per_kg_OPDYKE_1978_p853_857","TY_EXPLICIT_anticarcinogenic_class_rail_pistacia_lentiscus_var_chia_K562_leukemia_loutrari_2006_AND_limonene_anticarcinogenic_NOT_therapeutic_claim","TY_EXPLICIT_methyleugenol_carcinogen_class_rail_rodent_if_exposure_sufficiently_high","TY_EXPLICIT_IFRA_2009_methyleugenol_max_0_0004pct_leave_on_body_lotion_AND_SCCNFP_2002_max_0_0002pct_methyleugenol_REGULATORY_MUCH_MORE_CONSERVATIVE_THAN_TY_20pct","TY_EXPLICIT_LIMITED_AVAILABILITY","anacardiaceae_family_FIRST_singleton_in_wiki_urushiol_allergen_warning_fresh_plant_vs_EO_distinction_steam_distillation_strips"]
phototoxic
false
safety_level
caution
cap_derivation
TY_EXPLICIT_VERBATIM_20pct_adult_dermal_methyleugenol_carcinogen_DERIVED_PLUS_alpha_pinene_58_8_to_78_6_pct_EXTREME_DOMINANCE_PLUS_TY_EXPLICIT_VERBATIM_HAZARDS_MAY_CONTAIN_METHYLEUGENOL_PLUS_CONTRAINDICATIONS_NONE_KNOWN_PLUS_TY_EXPLICIT_VERBATIM_DERMAL_MAX_20PCT_BASED_ON_0_1PCT_METHYLEUGENOL_CONTENT_WITH_DERMAL_LIMIT_0_02PCT_METHYLEUGENOL_PROFILE_CHAPTER_14_PLUS_TY_EXPLICIT_VERBATIM_HIGH_ALPHA_PINENE_CONTENT_OXIDATION_AVOIDED_BY_STORAGE_DARK_AIRTIGHT_REFRIGERATOR_PLUS_MANDATORY_ANTIOXIDANT_AT_PRODUCTION_PLUS_alpha_pinene_autoxidation_skin_sensitization_class_rail_TY_EXPLICIT_PLUS_low_reproductive_toxicity_alpha_pinene_AND_beta_myrcene_AND_linalool_class_rail_NOT_hazardous_in_pregnancy_TY_EXPLICIT_PLUS_no_EO_direct_acute_toxicity_data_alpha_pinene_LD50_rats_2_1_3_2_3_7_g_per_kg_OPDYKE_1978_p853_857_PLUS_anticarcinogenic_class_rail_only_via_pistacia_lentiscus_var_chia_K562_leukemia_loutrari_2006_NOT_therapeutic_claim_PLUS_LIMONENE_anticarcinogenic_class_marker_PLUS_methyleugenol_carcinogen_class_rail_TY_explicit_rodent_if_exposure_sufficiently_high_PLUS_IFRA_2009_methyleugenol_max_0_0004pct_leave_on_body_lotion_PLUS_SCCNFP_2002_max_0_0002pct_methyleugenol_PLUS_eu_0_2pct_ifra_0_4pct_REGULATORY_MUCH_MORE_CONSERVATIVE_THAN_TY_20pct_PLUS_anacardiaceae_family_singleton_FIRST_in_wiki_class_rail_PLUS_chios_island_greek_pdo_protected_mastiha_traditional_heritage
oxidation_risk
high
max_dilution_2_6
5
drug_interactions
[]
max_dilution_6_12
10
shelf_life_months
18
max_dilution_adult
20
contraindicated_all
false
max_dilution_elderly
10
max_oral_dose_mg_day
200
max_dilution_sensitive
10
max_dilution_adult_face
10
contraindicated_children
false
contraindicated_pregnancy
false
max_dilution_child_under2
2.5
max_dilution_breastfeeding
10
max_dilution_pregnancy_1st
10
max_dilution_pregnancy_2nd
10
max_dilution_pregnancy_3rd
10
max_oral_dose_mg_day_pregnancy
0

Luận Giải Văn Cảnh

hazards

hazards: [TY_EXPLICIT_HAZARDS_MAY_CONTAIN_METHYLEUGENOL_p694, TY_EXPLICIT_CONTRAINDICATIONS_NONE_KNOWN_p694, TY_EXPLICIT_DERMAL_MAX_20pct_methyleugenol_carcinogen_cap_derived_0_1pct_methyleugenol_x_20pct_equals_0_02pct_methyleugenol_in_product_TY_dermal_limit_methyleugenol_chapter_14, TY_EXPLICIT_MANDATORY_REFRIGERATED_STORAGE_high_alpha_pinene_content_oxidation_avoided_by_storage_dark_airtight_refrigerator, TY_EXPLICIT_MANDATORY_ANTIOXIDANT_AT_PRODUCTION_BHT_or_alpha_tocopherol_addition_recommended, TY_EXPLICIT_alpha_pinene_autoxidation_can_cause_skin_sensitization_class_rail_chapter_14, TY_EXPLICIT_low_reproductive_toxicity_alpha_pinene_AND_beta_myrcene_AND_linalool_NOT_hazardous_in_pregnancy, TY_EXPLICIT_no_EO_direct_acute_toxicity_data_alpha_pinene_LD50_rats_2_1_3_2_3_7_g_per_kg_OPDYKE_1978_p853_857, TY_EXPLICIT_anticarcinogenic_class_rail_pistacia_lentiscus_var_chia_K562_leukemia_loutrari_2006_AND_limonene_anticarcinogenic_NOT_therapeutic_claim, TY_EXPLICIT_methyleugenol_carcinogen_class_rail_rodent_if_exposure_sufficiently_high, TY_EXPLICIT_IFRA_2009_methyleugenol_max_0_0004pct_leave_on_body_lotion_AND_SCCNFP_2002_max_0_0002pct_methyleugenol_REGULATORY_MUCH_MORE_CONSERVATIVE_THAN_TY_20pct, TY_EXPLICIT_LIMITED_AVAILABILITY, anacardiaceae_family_FIRST_singleton_in_wiki_urushiol_allergen_warning_fresh_plant_vs_EO_distinction_steam_distillation_strips]

storage

oxidation_risk: high

dilution

max_dilution_adult: 20

botanical

latin_name: Pistacia lentiscus L

chemistry

dominant_constituent: alpha-Pinene

commercial

availability: niche

oil_metadata

slug: mastic

safety_flags

phototoxic: FALSE

Tài Liệu Y Khoa Tham Khảo

  • B216 (Tisserand & Young 2014, "Essential Oil Safety, 2nd Ed.") — Ch.13 p.694 Mastic profile (this is primary source)
  • Lawrence 1995g p.19, p.69Pistacia lentiscus essential oil chemistry (cited in B216 Ch.13 p.694)
  • Magiatis et al 1999 — Mastic essential oil chemistry (cited in B216 Ch.13 p.694)
  • Opdyke 1978 p.853–857 — α-pinene acute oral LD50 rats 2.1, 3.2, 3.7 g/kg + acute dermal LD50 rabbits < 5 g/kg (cited in B216 Ch.13 p.694)
  • Loutrari, H., Magkouta, S., Pyriochou, A., et al 2006Pistacia lentiscus var. chia oil inhibited proliferation + angiogenesis of human leukemia K562 cells (cited in B216 Ch.13 p.694)
  • B216 α-Pinene profile Chapter 14 — autoxidation skin sensitization class-rail + low reproductive toxicity + acute toxicity LD50 data
  • B216 Methyleugenol profile Chapter 14 — rodent carcinogen + dermal limit 0.02% basis for T&Y 20% mastic cap derivation
  • B216 β-Myrcene profile Chapter 14 — low reproductive toxicity class-rail
  • B216 Linalool profile Chapter 14 — low reproductive toxicity + IFRA 2009 peroxide-control class-rail
  • B216 (+)-Limonene profile Chapter 14 — anticarcinogenic activity class marker
  • IFRA 2009 — methyleugenol max 0.0004% leave-on body-lotion regulatory
  • SCCNFP / European Commission 2002 — methyleugenol max 0.0002% regulatory