Lantana essential oil (Lantana camara L., Verbenaceae family) is a davanone-dominant Madagascan-chemotype flowering-tops EO with clean T&Y "None known × 2" safety profile and a CRITICAL EO-vs-plant-toxicity disambiguation rail. B216 Ch.13 p.647–648 cites Ngassoum et al 1999 Madagascan chemotype: davanone 15.9% + β-caryophyllene 12.0% + sabinene 9.0% + α-caryophyllene 6.2% + α-pinene 3.7% + linalool 3.4% + β-bisabolene 3.0% + 1,8-cineole 2.8% + bicyclogermacrene 2.6% + β-pinene 2.6% + δ-3-carene 2.3% + nerolidol 2.3% + camphene 2.0% + humulene epoxide 1.9% + cubebol 1.6% + (+)-limonene 1.6% + germacrene D 1.4% + caryophyllene epoxide II 1.2% + α-muurolene 1.2% + (E)-β-ocimene 1.1% + β-cubebene 1.0% + (E)-β-farnesene 1.0% + γ-terpinene 1.0%. Hazard signature: T&Y verbatim "Hazards: None known. Contraindications: None known." No T&Y dermal cap stated → framework default 5.0% applied. CRITICAL EO-vs-plant-toxicity rail (B216 EXPLICIT verbatim): "Consumption of Lantana camara by grazing animals causes acute hepatotoxicity. This is due to the presence of triterpenoids called LANTADENES, which are NOT present in the essential oil (Sharma et al 2007). Davanone is not hepatotoxic since davana oil, which contains 38.0% davanone, showed no signs of either acute or subacute toxicity in a 90 day feeding study in rats (Oser et al 1965; Opdyke 1976 p. 737)." — lantadenes-stay-with-plant-not-EO standard fundamental disambiguation rail (analogous to forskolin-not-in-EO coleus rail EO707, lantadenes are non-volatile pentacyclic triterpenoids that do NOT carry over into steam-distilled EO). Adverse skin reactions: B216 verbatim "No information was found for lantana oil or davanone." Acute toxicity: B216 verbatim "No information was found for lantana oil or for davanone, but see Hepatotoxicity above" — i.e. davana oil 90-day rat study at 38% davanone gave clean signal, by extrapolation lantana 15.9% davanone is acceptable. Carcinogenic potential: B216 verbatim "No information was found for lantana oil, but it contains no known carcinogens. β-Caryophyllene and α-caryophyllene display anticarcinogenic activity (see Constituent profiles, Chapter 14)" — caryophyllene-class anticarcinogenic-constituent-class rail (EO751 katrafay β-elemene class peer). Davanone marker rail (CRITICAL): Davanone is the dominant constituent shared with [[davana]] (Artemisia pallens davana oil 38% davanone) — class-shared marker bridging lantana → davana despite different families (Verbenaceae vs Asteraceae); davanone clean toxicity profile per Oser 1965 90-day rat study at 38% (davana) extrapolates to 15.9% (lantana) safe-by-extrapolation rail. Verbenaceae-family-aromatic class: Class-shared with [[lemon-verbena]] (Aloysia citrodora citral-rich) + [[vervain-european]] (Verbena officinalis) + [[gattilier]] (Vitex agnus-castus — chaste-tree EO704); however lantana chemistry is very distinct (davanone + caryophyllene-rich, NOT citral-rich). Madagascar-chemotype-specific rail: B216 cites Ngassoum 1999 Madagascan chemotype specifically; lantana grows pantropically and other-origin chemotypes (Asia, Caribbean, Florida, Australia) often differ chemistry significantly — Madagascan davanone-rich chemotype is the B216-validated profile; non-Madagascan oils may have different safety/chemistry. Closes Mini-Batch 23a → opens Mini-Batch 23b clean-vs-thujone-vs-oxidation-trio (lantana clean → lanyana thujone-hard-cap-pregnancy-contraindication → larch-needle latent-α-pinene-oxidation).
Tổng Quan
- Danh pháp khoa học
- Lantana camara L.
- Họ thực vật
- Verbenaceae
- Bộ phận dùng
- Flowering tops
- Phương pháp chiết xuất
- steam_distillation
- Màu sắc
- —
- Phân loại nốt hương
- Nốt Middle
- Hương thơm
- —
- Chemotype / Cultivar
- —
Các quốc gia sản xuất chính
Tình trạng tại Việt Nam
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Warm golden-earthy depth, dried botanical spice, sun-baked wild herbs, faintly sweet resinous undertone, cooling camphor whisper
Chiều sâu đất ấm vàng son, gia vị thảo mộc phơi khô, thảo dược hoang dã phơi nắng, tầng nền nhựa thơm ngọt nhẹ, thoáng long não dịu mát
2–4 giờ
Tên gọi tại Việt Nam
Pha Chế & Hòa Hợp
β-Caryophyllene (12%) acts as a selective CB2 receptor agonist, modulating inflammatory cytokine cascades and reducing prostaglandin synthesis via NF-κB pathway inhibition.
Ref: class-extrapolation from β-caryophyllene-rich peer oils; constituent confirmed in Ngassoum MB et al (1999) per Tisserand & Young 2014, Ch.13 p. 647–648
Davanone (15.9%), the dominant sesquiterpene ketone shared with davana oil, is traditionally associated with calming and grounding emotional support via limbic olfactory stimulation.
Ref: class-extrapolation from davana oil; Oser BL et al (1965) 90-day rat study via Opdyke DLJ (1976) p. 737 confirms davanone class safety; Tisserand & Young 2014, Ch.13 p. 647–648
Sesquiterpene ketone class (davanone) and sesquiterpene hydrocarbons (β-caryophyllene + α-caryophyllene combined ~18%) contribute to smooth-muscle relaxation via calcium-channel modulation.
Ref: class-extrapolation from davanone-class oils (davana); Tisserand & Young 2014, Ch.13 p. 647–648
β-Caryophyllene (12%) disrupts microbial cell membranes and inhibits biofilm formation; the combined sesquiterpene-rich Madagascan chemotype profile suggests broad-spectrum activity.
Ref: class-extrapolation from β-caryophyllene-containing oils; Ngassoum MB et al (1999) chemotype confirmed in Tisserand & Young 2014, Ch.13 p. 647–648
Combined anti-inflammatory action of β-caryophyllene and α-caryophyllene (~18% total) reduces cutaneous inflammation and histamine-mediated itch responses at topical concentrations.
Ref: class-extrapolation from β-caryophyllene-dominant oils; Tisserand & Young 2014, Ch.13 p. 647–648
β-Caryophyllene and α-caryophyllene are B216-recognised anticarcinogenic-class constituents; activity is in-vitro cell culture only — a constituent annotation, NOT a therapeutic claim for the whole EO.
Ref: Tisserand & Young 2014, Ch.13 p. 647–648; B216 constituent-class annotation EXPLICIT; NOT a therapeutic anti-cancer claim
AI-summary
No RCT-grade clinical evidence has been located specifically for Lantana camara EO (Madagascan chemotype). The sole controlled study (Oser BL et al 1965, 90-day rat feeding, 38% davanone davana oil, via Opdyke 1976) is a safety—not efficacy—study confirming no acute/subacute toxicity for the davanone class; it does not constitute therapeutic evidence for lantana. Sharma et al (2007) confirmed hepatotoxic lantadenes are non-volatile and do NOT transfer into the steam-distilled EO, resolving a key safety concern. All therapeutic ratings above 1 are based on constituent-class extrapolation (β-caryophyllene CB2 pharmacology, davanone sesquiterpene-ketone class). Traditional aromatherapy use as a calming, anti-inflammatory aromatic/topical; no RCT-grade clinical evidence for the EO itself.
NarrativeTâm trạng: Grounding, Balancing
Chakra
root
Ngũ hành
tho
| Phương pháp | Liều lượng | Ghi chú |
|---|---|---|
| Diffusion | 3–5 drops per 100 ml water | Dùng máy siêu âm 30–60 phút. Hỗ trợ tâm lý, giảm căng thẳng. Chỉ dùng chemotype Madagascar/Comoros/Nam Phi đã xác nhận — chemotype khác có hồ sơ an toàn khác biệt. |
| Topical massage | 1–2% in carrier oil (6–12 drops per 30 ml) | Pha trong dầu nền trung tính. Patch test 24h trước. Max dermal 5% adult; 1–2% là liều thực tế an toàn lâu dài. Không dùng cho trẻ em / phụ nữ có thai. |
| Inhalation (direct / personal inhaler) | 2–3 drops on tissue or inhaler stick | Hít trực tiếp 5–10 giây, 2–3 lần/ngày. Hỗ trợ tâm lý tại chỗ. Không hít liên tục kéo dài. |
| Bath | 3–5 drops dispersed in 1 tsp carrier or bath salt | Pha trong dầu nền hoặc muối tắm trước khi cho vào bồn. Ngâm tối đa 15–20 phút. Phụ nữ mang thai, trẻ em: không khuyến nghị. |
| Skincare blend | 0.5–1% in unscented cream or serum | Công thức dưỡng da chống viêm, làm dịu da khô/trưởng thành. Patch test 48h cho da nhạy cảm. Chỉ dùng Madagascan-verified chemotype. |
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