SYMELab
The Perfumer's Grimoire

Tinh dầu Cúc Ngải

Feverfew

Tanacetum parthenium (L.) Sch. Bip.

Top/MiddleHoa

Băng não cắt lạnh sắc nét, thảo dược y tế mát lạnh, hoa cúc xanh tươi nồng nàn, sáng trắng sáp tinh khiết, xuyên thấu và khắc khổ

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Tóm Tắt Khoa Học

Từ Thư Viện Kinh Điển
  1. Tanacetum parthenium (L.) Sch. Bip. (syn. Chrysanthemum parthenium, Asteraceae / Compositae) — steam distillate from leaves. Camphor-dominant chemotype (camphor 28.0–44.2% + (E)-chrysanthenyl acetate 22.9–30.2%).
  2. Hazards: Moderate neurotoxicity, based on camphor content. Contraindications (all routes): Pregnancy, breastfeeding. (T&Y verbatim p.580). Maximum adult daily oral dose 318 mg. Maximum dermal use level 10%.
  3. Max dermal 10% derived from T&Y Ch.14 camphor dermal limit 4.5% ÷ 44.2% worst-case camphor = 10.2% ≈ 10% whole-oil. Max oral 318 mg/day derived from camphor 2 mg/kg/day × 70 kg ÷ 44.2% = 316.7 ≈ 318 mg. Non-phototoxic (Asteraceae leaf steam distillate, no furocoumarin pathway).
  4. Contraindicated pregnancy + breastfeeding ALL routes — T&Y verbatim (camphor-driven neurotoxicity + historical abortifacient folk use; Asteraceae Tanacetum genus also associated with reproductive-toxicity signals).
  5. Key rails: EO vs HERBAL-EXTRACT CRITICAL — feverfew EO is camphor-dominant aromatherapy oil ≠ feverfew dried-leaf / parthenolide-standardized migraine supplement (Cady 2011, Diener 2005 clinical trials). Parthenolide (sesquiterpene lactone) is too heavy for atmospheric steam distillation → stays in still residue → absent from EO. Do NOT extrapolate herbal migraine efficacy to EO use. CAMPHOR-DOMINANT peer class with [[ho-leaf-camphor-ct]] 84.1% + [[lavender-spanish]] 56.2% + [[rosemary-camphor-ct]] + [[mugwort-camphor-ct]] 11.4% per T&Y Table 13.2 p.346.
🌿
Thận trọngNốt Top/MiddleCamphoraceous-herbal-bitter with distinct chrysanthemum floral-herbal undertone

Feverfew

Tinh dầu Cúc Ngải (Feverfew)

Tanacetum parthenium (L.) Sch. Bip.

Tinh dầu Cúc Ngải (Feverfew) — Camphoraceous-herbal-bitter with distinct chrysanthemum floral-herbal undertone

⚠️Tinh dầu này cần thận trọng khi sử dụng. Đọc kỹ hướng dẫn an toàn.

Tổng Quan

Danh pháp khoa học
Tanacetum parthenium (L.) Sch. Bip.
Họ thực vật
Asteraceae
Bộ phận dùng
Leaves
Phương pháp chiết xuất
steam_distillation
Màu sắc
Phân loại nốt hương
Nốt Top/Middle
Hương thơm
Chemotype / Cultivar

Tình trạng tại Việt Nam

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Phân loại nốt
Top-Middle
Cường độ
4/5
Độ bền trên da
2–4 giờ
Họ hương
Camphoraceous-herbal-bitter with distinct chrysanthemum floral-herbal undertone
Hương đầu (Opening)(0–15 phút)

Piercing camphorous bite, sharp medicinal herbs, cool green chrysanthemum, waxy bright clarity, penetrating and austere

Hương giữa (Heart)(15–60 phút)

Băng não cắt lạnh sắc nét, thảo dược y tế mát lạnh, hoa cúc xanh tươi nồng nàn, sáng trắng sáp tinh khiết, xuyên thấu và khắc khổ

Hương nền (Drydown)(1–4 giờ)

2–4 giờ

Cường độ hương
4/5
Da khô
2/5

Da dầu/mụn
3/5

Da lão hóa
2/5

Da thường
3/5

Da nhạy cảm
1/5

Da hỗn hợp
3/5

Nhập khẩuImported

Tên gọi tại Việt Nam

Tinh dầu Cúc Ngải (Feverfew)

Pha Chế & Hòa Hợp

analgesic — topical counterirritant

Camphor activates TRPV1 and TRPM8 thermoreceptors, producing an initial warming followed by a cooling sensation that modulates peripheral pain perception at the application site.

Ref: Tisserand & Young 2014, Ch.13 p.580; Ch.14 Camphor

rubefacient

Camphor-mediated local vasodilation increases cutaneous blood flow, producing the characteristic warming flush used in muscle and joint applications.

Ref: Tisserand & Young 2014, Ch.14 Camphor; Table 13.2 p.346 (high-camphor oils)

respiratory decongestant

Camphor stimulates TRPM8 cold receptors in upper-airway epithelium, promoting a sensation of improved airflow and mild secretolytic effect during steam inhalation.

Ref: Tisserand & Young 2014, Ch.14 Camphor

antispasmodic

Monoterpene constituents including camphene, bornyl acetate, and pinenes contribute mild smooth muscle relaxant activity consistent with class-level evidence for Asteraceae monoterpene-rich EOs.

Ref: class-extrapolation from camphor-rich Asteraceae oils (Tisserand & Young 2014, Ch.13 p.580)

anti-inflammatory (limited — EO, not herbal extract)

The sesquiterpene lactone parthenolide responsible for herbal extract anti-inflammatory and migraine-prophylaxis activity is largely absent from steam-distilled EO; camphor contributes only marginal COX pathway modulation.

Ref: Tisserand & Young 2014, Ch.13 p.580 (EO-vs-herb distinction flagged)

insect repellent

Camphor and associated monoterpenes exert insect-deterrent effects via olfactory receptor interference, consistent with class evidence for camphor-dominant EOs.

Ref: class-extrapolation from camphor-rich monoterpene EOs (Tisserand & Young 2014, Ch.14 Camphor)

AI-summary

All three human trials cited in §13 — Cady et al. 2011 (MIG-99 RCT), Diener et al. 2005 (MIG-99 RCT), and Pattrick et al. 1989 (crossover trial) — studied standardized MIG-99 feverfew HERBAL EXTRACT standardized to parthenolide content, not steam-distilled essential oil. This evidence CANNOT be extrapolated to the EO because parthenolide (the pharmacologically active sesquiterpene lactone) is largely absent from the steam distillate. No RCT-grade clinical evidence for feverfew EO specifically has been located. Topical analgesic and rubefacient claims for the EO rest on camphor constituent class-evidence (T&Y Ch.14) and traditional aromatherapy use rather than direct EO trials.

Narrative

Tâm trạng: Stimulating, Balancing

clarityfocusalertnesstension-releaseinvigorationmental-freshness

Chakra

third-eye

Ngũ hành

kim

Phương phápLiều lượngGhi chú
Topical massage1–3% in carrier oil (max 10% adult)Blend in jojoba or fractionated coconut for analgesic massage; avoid face and mucous membranes. Contraindicated in pregnancy. Start at 1% for first use.
Cold compress3–5 drops in 500ml cold waterApply wrung cloth to temples or forehead for tension headache. Do not apply neat. Cold compress preferred near head to avoid camphor-flush discomfort.
Diffusion3–4 drops in 100ml waterDiffuse intermittently (30 min on / 30 min off) for respiratory clearance. Avoid prolonged diffusion in small unventilated spaces due to camphor concentration.
Inhalation (steam)2–3 drops in bowl of hot waterTent head with towel for 5–7 minutes; eyes closed. Supports upper respiratory clearance. Avoid during pregnancy or in children under 6 years (camphor).
Warm compress4–5 drops in 500ml warm waterApply to joints or lower back for rubefacient effect; limit to 15 minutes. Avoid near face or mucous membranes.

Dầu nền phù hợp

JojobaLiquid wax with excellent skin compatibility; neutral odor allows camphor-forward character of feverfew EO to express; long shelf life stabilizes the blend.
Fractionated coconut oilLightweight, non-greasy carrier ideal for analgesic massage blends; rapid dermal penetration aids camphor delivery to muscle and joint tissue.
Sweet almond oilModerately rich emollient suitable for muscle-relief massage; oleic acid base complements rubefacient activity of camphor-dominant blend.
Arnica-infused sunflower oilTraditional pairing for topical analgesic and anti-bruising applications; arnica sesquiterpene lactones complement the anti-inflammatory positioning of feverfew EO.

Kết hợp tốt với

HerbaceousGreenFloralWoody

Blend kinh điển

[Tisserand & Young] Ch.13 p.580 (Feverfew); Ch.14 Camphor; Table 13.2 p.346 (high-camphor oils)
[Lawrence BM] chemistry profile (cited in T&Y)
[Cady RK, Goldstein J, Nett R, Mitchell R, Beach ME, Browning R] MIG-99 feverfew extract migraine prophylaxis RCT (HERBAL EXTRACT, NOT EO)
[Diener HC, Pfaffenrath V, Schnitker J, Friede M, Henneicke-von Zepelin HH] MIG-99 feverfew extract migraine RCT (HERBAL EXTRACT, NOT EO)
[Pattrick M, Heptinstall S, Doherty M] feverfew crossover migraine trial (HERBAL EXTRACT)

An Toàn

Giới hạn da tối đa

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Giới hạn IFRA

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Thai kỳ & Cho con bú

Tam cá nguyệt 1Unknown
Tam cá nguyệt 2Unknown
Tam cá nguyệt 3Unknown

Giới hạn độ tuổi

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Bảo quản

Bảo quản nơi tối, mát

Thông tin chỉ mang tính tham khảo, không thay thế tư vấn y tế chuyên nghiệp. SYMELab v2.0

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Hồ Sơ Hoá Học Chi Tiết
§3 Chemical Profile — chemotype, constituent ranges, adulteration
Constituent%
Camphor28.0–44.2%
(E)-Chrysanthenyl acetate22.9–30.2%
Camphene5.4–7.7%
Germacrene D0.7–4.6%
p-Cymene0.1–3.6%
(E)-β-Farnesene0.4–3.2%
β-Caryophyllene0.6–3.1%
β-Pinene0.4–2.8%
Chrysanthenone0.6–2.6%
trans-Chrysanthenoltr–2.3%
α-Pinene0.3–2.2%
Bornyl acetate0.3–2.1%
β-Cubebenetr–1.9%
Sabinene0.1–1.6%
(E)-Chrysanthenol0.1–1.2%

Chemistry insights

  • Camphor 28.0–44.2% dominant — bicyclic monoterpene ketone, moderate neurotoxicity driver. Worst-case 44.2% drives safety caps via T&Y Ch.14 camphor limits (2 mg/kg/day oral + 4.5% dermal — derived from adult single-dose oral NOAEL + dermal sensitization threshold).
  • (E)-Chrysanthenyl acetate 22.9–30.2% — monoterpene ester, chrysanthemum-genus-characteristic marker (cf. Chrysanthemum / Tanacetum distinction chemosystematic signal). Generally mild safety profile at this %.
  • Camphene 5.4–7.7% + α-Pinene 0.3–2.2% + β-Pinene 0.4–2.8% — low monoterpene-hydrocarbon fraction; autoxidation risk LOW-MEDIUM (camphor + ester fractions dominate).
  • Thujone ABSENT (critical differentiation from [[tansy]] T. vulgare — thujone 66–81% → contraindicated oral). Feverfew chemotypes do NOT contain significant thujone — but verify on CoA for adulteration detection.
  • Sesquiterpene lactones (parthenolide, santamarine, reynosin) ABSENT from EO — these are non-volatile heavy compounds (parthenolide MW 248, melting point 116°C) that stay in still residue during steam distillation. Present in dried-leaf herbal extract NOT in EO. This is the critical disambiguation point.
Công Dụng Trị Liệu Chi Tiết
§10 Therapeutic Uses — skin, emotional, physical, respiratory
  • Modern aromatherapy: NICHE ONLY — camphor-driven aromatherapy applications (rare due to safer camphor-dominant alternatives like [[rosemary-cineole-ct]] for respiratory). Not a foundation oil.
  • Traditional (DRIED HERB, NOT EO): Feverfew dried leaves have long history for migraine prophylaxis, fever reduction, menstrual regulation. Modern clinical evidence supports dried-herb/parthenolide extract for migraine prevention (Cady et al 2011 MIG-99 trial, Diener et al 2005). THIS EVIDENCE IS FOR PARTHENOLIDE-STANDARDIZED EXTRACT, NOT EO.
  • Emotional / energetic framing: Cooling camphoraceous + bitter-green — traditional "cooling" herb archetype.
  • Perfumery: Rarely used — camphor restriction + herbal bitterness.
Năng Lượng & Ngũ Hành
§11 Energetics — TCM, Ayurveda, aromatic energetics
  • Five-element: Kim (Metal — camphor + ester) with Mộc (Wood — green-herbal) accent.
  • TCM: Cooling, bitter — traditional "fever-reducing" association (hence common name).

Dữ Liệu Kỹ Thuật Y Khoa

§14 Renderer Contract — Tisserand & Young V2.2

Thông Số Định Lượng

hazards
["moderate_neurotoxicity_camphor","contraindicated_pregnancy_breastfeeding"]
phototoxic
false
safety_level
caution
cap_derivation
ty_camphor_44.2pct_neurotoxicity_cap
oxidation_risk
low_medium
drug_interactions
[]
shelf_life_months
24
max_dilution_adult
10
contraindicated_all
false
max_dilution_elderly
5
max_oral_dose_mg_day
318
max_dilution_child_2_6
1
max_dilution_sensitive
2
max_dilution_adult_face
5
max_dilution_child_6_12
2
contraindicated_children
false
contraindicated_pregnancy
true
max_dilution_child_under2
0
max_dilution_pregnancy_1st
0
max_dilution_pregnancy_2nd
0
max_dilution_pregnancy_3rd
0

Tài Liệu Y Khoa Tham Khảo

  • Tisserand & Young (2014) Essential Oil Safety 2nd ed — Ch.13 p.580 (Feverfew); Ch.14 Camphor; Table 13.2 p.346 (high-camphor oils)
  • Lawrence BM (1999e) — chemistry profile (cited in T&Y)
  • Cady RK, Goldstein J, Nett R, Mitchell R, Beach ME, Browning R (2011) — MIG-99 feverfew extract migraine prophylaxis RCT (HERBAL EXTRACT, NOT EO)
  • Diener HC, Pfaffenrath V, Schnitker J, Friede M, Henneicke-von Zepelin HH (2005) — MIG-99 feverfew extract migraine RCT (HERBAL EXTRACT, NOT EO)
  • Pattrick M, Heptinstall S, Doherty M (1989) — feverfew crossover migraine trial (HERBAL EXTRACT)