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Tinh dầu Copaiba

Copaiba

Copaifera langsdorfii Desf., Copaifera officinalis (Jacq.) L.

BaseGỗ

Gỗ ấm khô thoáng, thoảng cay như đinh hương xa xôi, ngọt nhựa cây trầm tĩnh, nền rừng mát sâu lúc hoàng hôn, yên ắng vững chãi

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Tóm Tắt Khoa Học

Từ Thư Viện Kinh Điển
  1. Copaifera langsdorfii Desf. + Copaifera officinalis (Jacq.) L. (Fabaceae / Leguminosae) — essential oil steam-distilled from BALSAM tapped from tree wood (not wood steam distillate directly). 2-species commercial supply from South America (Brazil + Venezuela).
  2. Hazards: None known. Contraindications: None known. Clean T&Y profile — both species.
  3. Dermal cap 5.0% (framework default). Non-phototoxic. 8% on 25 volunteers = non-irritating, non-sensitizing (Opdyke 1973 p.1075). Undiluted irritating to rabbits at full strength.
  4. Acute toxicity: Oral LD50 rats > 5 g/kg; dermal LD50 rabbits > 5 g/kg (Opdyke 1973 p.1075). Reproductive toxicity study: C. duckei 2.5% vaginal cream 28.6 mg/kg (= 10× human dose) non-teratogenic in female rats (Lima et al 2011).
  5. Key rail: "Copaiba balsam does not carry the same risk of skin reactions as Peru balsam" (T&Y verbatim) — disambiguation vs [[balsam-peru]] which contains benzyl benzoate + benzyl cinnamate sensitizers. β-Caryophyllene + α-caryophyllene antitumoral activity (Ch.14); in vitro B16F10 melanoma cytotoxicity + reduced lung metastasis (Lima et al 2003) — constituent-level in-vitro signal, NOT clinical anticancer claim.
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Thận trọngNốt BaseWoody-balsamic-ambery-peppery (β-caryophyllene driven)

Copaiba

Tinh dầu Copaiba (Nhựa gỗ copaiba)

Copaifera langsdorfii Desf., Copaifera officinalis (Jacq.) L.

Tinh dầu Copaiba (Nhựa gỗ copaiba) — Woody-balsamic-ambery-peppery (β-caryophyllene driven)

⚠️Tinh dầu này cần thận trọng khi sử dụng. Đọc kỹ hướng dẫn an toàn.

Tổng Quan

Danh pháp khoa học
Copaifera langsdorfii Desf., Copaifera officinalis (Jacq.) L.
Họ thực vật
Fabaceae
Bộ phận dùng
Balsam from wood
Phương pháp chiết xuất
balsam_steam_distillation
Màu sắc
Phân loại nốt hương
Nốt Base
Hương thơm
Chemotype / Cultivar

Tình trạng tại Việt Nam

Xem chi tiết

Phân loại nốt
Base
Cường độ
2/5
Độ bền trên da
2–4 giờ
Họ hương
Woody-balsamic-ambery-peppery (β-caryophyllene driven)
Hương đầu (Opening)(0–15 phút)

Warm dry timber, faint whisper of clove-spice, quiet balsamic sweetness, cool forest floor at dusk, deeply still and grounding

Hương giữa (Heart)(15–60 phút)

Gỗ ấm khô thoáng, thoảng cay như đinh hương xa xôi, ngọt nhựa cây trầm tĩnh, nền rừng mát sâu lúc hoàng hôn, yên ắng vững chãi

Hương nền (Drydown)(1–4 giờ)

2–4 giờ

Cường độ hương
2/5
Da khô
4/5

Da dầu/mụn
2/5

Da lão hóa
4/5

Da thường
3/5

Da nhạy cảm
5/5

Da hỗn hợp
3/5

Nhập khẩuImported

Tên gọi tại Việt Nam

Tinh dầu Copaiba (Nhựa gỗ copaiba)

Pha Chế & Hòa Hợp

anti-inflammatory

β-Caryophyllene, the dominant sesquiterpene hydrocarbon in Copaifera spp. oil, acts as a selective CB2 receptor agonist, down-regulating NF-κB-mediated prostaglandin and cytokine cascades to suppress peripheral inflammation.

Ref: Tisserand & Young 2014, Ch.13 p.545–546; Gramosa & Silveira (2005); Stashenko et al (1995); CB2 mechanism as class-extrapolation from β-caryophyllene constituent pharmacology

analgesic

CB2 receptor engagement by β-caryophyllene attenuates peripheral nociceptive sensitization and reduces pro-inflammatory mediators that drive inflammatory pain, yielding a secondary analgesic effect without direct opioid-receptor binding.

Ref: class-extrapolation from β-caryophyllene constituent pharmacology; Tisserand & Young 2014, Ch.13 p.545–546

anticarcinogenic (preclinical, in vitro/in vivo)

Copaiba oleoresin constituents demonstrated cytotoxic activity against B16F10 murine melanoma cells and statistically significant reduction of experimental lung metastasis colonies.

Ref: Lima et al (2003)

antimicrobial — broad spectrum

Sesquiterpene hydrocarbon-rich fraction (β-caryophyllene, γ-muurolene, δ-cadinene) disrupts microbial membrane integrity via hydrophobic intercalation, consistent with antimicrobial activity observed across this constituent class.

Ref: class-extrapolation from sesquiterpene hydrocarbon-class EOs; Gramosa & Silveira (2005); Stashenko et al (1995)

vulnerary (wound healing / tissue repair)

Anti-inflammatory sesquiterpenes reduce oxidative tissue damage at the wound site; the resinous balsam matrix provides a protective occlusive barrier supporting re-epithelialization.

Ref: Tisserand & Young 2014, Ch.13 p.545–546; traditional Amazonian pharmacopoeia (Copaifera spp. balsam topical use)

expectorant / respiratory mucolytic

Volatile sesquiterpene constituents inhaled from the steam-distilled fraction may stimulate mucociliary transport and reduce bronchial secretion viscosity via reflex stimulation of respiratory mucosa.

Ref: Tisserand & Young 2014, Ch.13 p.545–546; traditional use — no controlled respiratory trial in §13 citations

AI-summary

Strongest preclinical evidence: Lima et al (2003) demonstrated cytotoxicity of copaiba oleoresin against B16F10 murine melanoma cells in vitro and a statistically significant reduction of lung metastasis colonies in an experimental animal model. This is in vitro/in vivo preclinical data applicable to the full oleoresin — not exclusively the steam-distilled EO fraction — and does not constitute clinical therapeutic evidence. Safety data from Opdyke (1973) reported an oral LD50 > 5 g/kg (rat) and a 48-hour repeat insult patch test at 8% on 30 volunteers produced no irritation or sensitization reactions. Lima et al (2011) assessed reproductive toxicity of C. duckei oleoresin administered orally — a safety study only, not a therapeutic endpoint. No RCT-grade clinical aromatherapy trial was identified in the §13 citations provided.

Narrative

Tâm trạng: Grounding, Calming

groundingcalminner stillnessresiliencecontemplationsteadiness

Chakra

root

Ngũ hành

tho

Phương phápLiều lượngGhi chú
Topical massage1–5% in carrier oil (T&Y max dermal 5% adult)Dilute in jojoba or sweet almond oil; target joints, lower back, inflamed muscles. Avoid mucous membranes; max 1% on broken skin.
Skincare (leave-on formulation)0.5–2% in cream, balm, or serum baseFor eczema, psoriasis, rosacea; use 1% max on sensitive/compromised skin; blend with rosehip oil base for mature or scar-tissue repair.
Diffusion3–5 drops per 100 ml water in ultrasonic diffuserDeep woody-balsamic aroma; blend with frankincense or sandalwood. Sessions 30–60 min with ventilation breaks.
Steam inhalation2–3 drops in bowl of steaming waterCover head with towel; keep eyes closed; 5–10 min sessions. Avoid in children under 5 or during acute asthma exacerbation.
Warm compress3–4 drops dispersed in 500 ml warm water via solubilizerApply wrung cloth to arthritic joints or lower back for 10–15 min. Monitor skin temperature; remove if discomfort. Up to twice daily.

Dầu nền phù hợp

Jojoba oilNon-comedogenic wax ester mimicking sebum; excellent oxidative stability complements copaiba's sesquiterpene-heavy profile; suited to all skin types including oily and sensitive.
Sweet almond oilMild oleic-acid-rich carrier with gentle emollient action and fast absorption; enhances anti-inflammatory skin benefits without heavy occlusive residue; well-tolerated by sensitive skin.
Rosehip seed oilHigh linoleic acid and natural retinoid precursors synergize with copaiba's vulnerary and anti-inflammatory properties for scar tissue, mature, or photo-damaged skin.
Fractionated coconut oilLightweight, odourless MCT base with long shelf life; excellent for body massage blends requiring rapid absorption and consistent dilution control.

Kết hợp tốt với

ResinousSpicyEarthyFloral

Blend kinh điển

[Tisserand & Young] Ch.13 p.545–546 (Copaiba)
[Opdyke DL] Copaiba Balsam Oil — p.1075 (LD50 + volunteer testing)
[Gramosa & Silveira] C. langsdorfii chemistry
[Stashenko et al] C. officinalis chemistry
[Lima et al] B16F10 melanoma cytotoxicity + metastasis reduction

An Toàn

Giới hạn da tối đa

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Giới hạn IFRA

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Thai kỳ & Cho con bú

Tam cá nguyệt 1Unknown
Tam cá nguyệt 2Unknown
Tam cá nguyệt 3Unknown

Giới hạn độ tuổi

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Bảo quản

Bảo quản nơi tối, mát

Thông tin chỉ mang tính tham khảo, không thay thế tư vấn y tế chuyên nghiệp. SYMELab v2.0

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Hồ Sơ Hoá Học Chi Tiết
§3 Chemical Profile — chemotype, constituent ranges, adulteration

Two species, two chemotypes — chemistry diverges significantly

C. langsdorfii — Gramosa & Silveira 2005

Constituent%
β-Caryophyllene53.3%
Germacrene B8.7%
β-Selinene6.5%
α-Caryophyllene (humulene)6.1%
γ-Elemene4.8%
α-Selinene4.5%
β-Elemene4.4%
γ-Muurolene2.7%
Cubebene2.2%
δ-Cadinene1.7%
α-Guaiene1.7%
Germacrene D1.4%

C. officinalis — Stashenko et al 1995

Constituent%
β-Caryophyllene24.7%
α-Copaene20.7%
δ-Cadinene7.7%
γ-Cadinene5.5%
Cedrol4.8%
α-Selinene4.1%
α-Ylangene2.9%
β-Cubebene2.7%
α-Caryophyllene2.7%
Germacrene D2.3%
α-Cubebene2.0%
(−)-allo-Aromadendrene1.8%
δ-Elemene1.6%
β-Selinene1.5%
γ-Muurolene1.2%
β-Bisabolol1.1%
Himachalene1.1%

Chemistry insights

  • Sesquiterpene-hydrocarbon dominated — both species are ~100% sesquiterpene profile (no significant monoterpene, alcohol, ester, or phenol fractions).
  • β-Caryophyllene is the universal signature — dominant in langsdorfii (53.3%) + major in officinalis (24.7%). Known CB2 cannabinoid receptor agonist (functional food literature).
  • Officinalis inverts the monoconstituent-dominance pattern with α-copaene 20.7% as co-dominant, while langsdorfii has no constituent above β-caryophyllene.
  • Cedrol 4.8% in officinalis (not in langsdorfii) — contributes woody-ambery facet.
  • Anticarcinogenic constituents: β-caryophyllene + α-caryophyllene + β-elemene + germacrene D + α-copaene all display anticarcinogenic activity per Ch.14 Constituent profiles (in vitro signal — NOT clinical claim).
  • No concerning constituents: no furocoumarins, no phenols, no aldehydes, no hepatotoxic terpene ketones. Clean sesquiterpene chassis.
Công Dụng Trị Liệu Chi Tiết
§10 Therapeutic Uses — skin, emotional, physical, respiratory
  • Modern aromatherapy: Anti-inflammatory (β-caryophyllene CB2 agonist mechanism), respiratory, urinary tract, skin inflammatory support. Base-note fixative in blends.
  • Traditional: Long history in South American traditional medicine — balsam + EO both used. Three patents filed relating to cosmetic uses (T&Y Comments).
  • Emotional / energetic framing: Grounding, stabilizing, centering (base-note sesquiterpene chassis shared with patchouli + vetiver).
  • Perfumery: Base fixative for woody-balsamic-oriental accords.
Năng Lượng & Ngũ Hành
§11 Energetics — TCM, Ayurveda, aromatic energetics
  • Five-element: Thổ-Kim (Earth–Metal — grounding + resinous + balsamic).
  • Base-note stabilizing archetype.

Dữ Liệu Kỹ Thuật Y Khoa

§14 Renderer Contract — Tisserand & Young V2.2

Thông Số Định Lượng

hazards
[]
phototoxic
false
safety_level
safe
cap_derivation
framework_default
oxidation_risk
low
drug_interactions
[]
shelf_life_months
36
max_dilution_adult
5
contraindicated_all
false
max_dilution_elderly
5
max_oral_dose_mg_day
700
max_dilution_child_2_6
3
max_dilution_sensitive
5
max_dilution_adult_face
5
max_dilution_child_6_12
5
contraindicated_children
false
contraindicated_pregnancy
false
max_dilution_child_under2
2
max_dilution_pregnancy_1st
5
max_dilution_pregnancy_2nd
5
max_dilution_pregnancy_3rd
5

Tài Liệu Y Khoa Tham Khảo

  • Tisserand & Young (2014) Essential Oil Safety 2nd ed — Ch.13 p.545–546 (Copaiba)
  • Opdyke DL (1973) Food and Cosmetics Toxicology 11 — Copaiba Balsam Oil — p.1075 (LD50 + volunteer testing)
  • Gramosa & Silveira (2005) — C. langsdorfii chemistry
  • Stashenko et al (1995) — C. officinalis chemistry
  • Lima et al (2003) — B16F10 melanoma cytotoxicity + metastasis reduction
  • Lima et al (2011) — C. duckei oleoresin reproductive toxicity study