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Tinh dầu lá Combava

Combava Leaf

Citrus hystrix DC

TopCam chanh

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Tóm Tắt Khoa Học

Từ Thư Viện Kinh Điển
  1. Citrus hystrix DC (Rutaceae) — leaves steam-distilled. Common names kaffir lime / makrut lime / leech-lime / Mauritius papeda / swangi (Southeast Asian cuisine staple).
  2. Hazards: None known. Contraindications: None known. Clean T&Y profile.
  3. Dermal cap 5.0% (framework default). Non-phototoxic (Rutaceae LEAF steam distillate — zero furocoumarin pathway).
  4. Chemistry: citronellal 58.9–81.5% dominant + citronellyl acetate 0.9–5.1% + isopulegol 0.3–4.9% + sabinene 1.6–4.8% + linalool 2.9–4.7% (Lawrence p.122). Chemistry completely inverted from [[combava-fruit]] (fruit peel citronellal only 0.4–16.8% + β-pinene dominant 25.9–31.5% vs leaf β-pinene 0.2–1.5%).
  5. Key rails: Same-species cross-variant rail vs [[combava-fruit]] — DIFFERENT plant part = DIFFERENT chemistry + DIFFERENT olfactory profile + DIFFERENT culinary role; verify plant part on supplier CoA. Non-phototoxic leaf-steam-distillate rail. Citronellal-dominant-oil peer class rail (joins [[citronella-java]] + [[citronella-sri-lanka]] + [[lemongrass]] + [[melissa]] — shared citronellal/citral aldehyde-rich safety pattern).
🌿
Thận trọngNốt TopCitrus-green-aldehydic with sharp lime-leaf character + herbaceous undertone

Combava Leaf

Tinh dầu lá Combava (Kaffir / Makrut lime leaf)

Citrus hystrix DC

Tinh dầu lá Combava (Kaffir / Makrut lime leaf) — Citrus-green-aldehydic with sharp lime-leaf character + herbaceous undertone

⚠️Tinh dầu này cần thận trọng khi sử dụng. Đọc kỹ hướng dẫn an toàn.

Tổng Quan

Danh pháp khoa học
Citrus hystrix DC
Họ thực vật
Rutaceae
Bộ phận dùng
Leaves
Phương pháp chiết xuất
steam_distillation
Màu sắc
Phân loại nốt hương
Nốt Top
Hương thơm
Chemotype / Cultivar

Tình trạng tại Việt Nam

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Phân loại nốt
Top
Cường độ
4/5
Độ bền trên da
2–4 giờ
Họ hương
Citrus-green-aldehydic with sharp lime-leaf character + herbaceous undertone
Hương đầu (Opening)(0–15 phút)

Bright lemon-fresh, clean aldehydic sparkle, faint rosy undertow beneath citrus clarity, cool green leaf whisper, diffusive and airy

Hương giữa (Heart)(15–60 phút)

Chanh sáng tinh khôi, lấp lánh trong sạch như buổi sớm, dư hương hoa hồng khẽ thoảng bên dưới làn trong suốt, lá xanh mát lạnh thì thầm, lan tỏa nhẹ như gió sớm

Hương nền (Drydown)(1–4 giờ)

2–4 giờ

Cường độ hương
4/5
Da khô
2/5

Da dầu/mụn
4/5

Da lão hóa
2/5

Da thường
3/5

Da nhạy cảm
2/5

Da hỗn hợp
4/5

Nhập khẩuImported

Tên gọi tại Việt Nam

Tinh dầu lá Combava (Kaffir / Makrut lime leaf)

Pha Chế & Hòa Hợp

antimicrobial — broad spectrum

Monoterpene hydrocarbons (principally sabinene and β-pinene) disrupt bacterial cell membranes and inhibit enzymatic activity across Gram-positive and Gram-negative organisms.

Ref: class-extrapolation from Citrus leaf oils (Rutaceae family); Tisserand & Young 2014, Ch.13 p.545

chemopreventive / antiproliferative

In-vitro cytotoxic activity against KB (human oral epidermoid carcinoma) and P388 (murine leukemia) cell lines attributed to the combined monoterpene and oxygenated constituent profile.

Ref: Manosroi et al (2005)

insect repellent

Citronellal and monoterpene constituents interfere with insect olfactory receptor binding and contact deterrence, masking host-seeking cues at sub-threshold concentrations.

Ref: class-extrapolation from citronella oil (citronellal class); Tisserand & Young 2014, Ch.13 p.545

anxiolytic / mood-uplifting

Fresh citrus-herbal aroma modulates limbic-system olfactory pathways, consistent with psychophysiological responses documented across the broader Citrus leaf oil class.

Ref: class-extrapolation from citrus leaf oils (Rutaceae family)

antifungal

Monoterpene-rich profile (sabinene, β-pinene) impairs fungal cell wall integrity and ergosterol biosynthesis, consistent with other Citrus leaf EOs in the Rutaceae family.

Ref: class-extrapolation from Citrus leaf oils (Rutaceae family)

anti-inflammatory

Oxygenated monoterpenes and sabinene may suppress NF-κB pathway activation and prostaglandin synthesis at therapeutic topical application concentrations.

Ref: class-extrapolation from Citrus leaf oils (Rutaceae family)

AI-summary

No RCT-grade clinical evidence specific to Combava leaf essential oil has been located. The strongest available data is an in-vitro chemopreventive study: Manosroi et al (2005) reported cytotoxic IC50 activity against KB (human oral epidermoid carcinoma) and P388 (murine leukemia) cell lines, suggesting antiproliferative potential attributable to the oil's constituent profile. Chemistry characterisation is documented in Lawrence (p.122). All remaining therapeutic ratings are extrapolated from the broader Citrus leaf oil class within Rutaceae. Traditional aromatherapy and ethnobotanical use in Southeast Asian practice (Thailand, Indonesia, Cambodia) is well-established, but controlled human trials are absent. Traditional aromatherapy use; no RCT-grade clinical evidence located beyond the single in-vitro study above.

Narrative

Tâm trạng: Uplifting, Calming

clarityrefreshmentjoylightnessrenewalfocus

Chakra

solar

Ngũ hành

moc

Phương phápLiều lượngGhi chú
Diffusion3–5 drops in 100 ml water30–60 minute sessions for mood uplift and ambient antimicrobial effect. Blends well with lemongrass or bergamot FCF. Ventilate room between sessions.
Topical massage1–2% in carrier oil (max 5% adult per T&Y)Preferred carriers: jojoba or fractionated coconut. Avoid on hypersensitive or broken skin. Patch test recommended. Keep well below 5% adult dermal ceiling.
Direct inhalation1–2 drops on tissue or cupped palm5–10 minute sessions for quick mood lift or mental clarity. Not recommended for children under 10 or those with reactive airways without practitioner guidance.
Room spray15–20 drops per 100 ml distilled water + dispersantShake before use. Suitable as insect-deterrent spray; synergises with citronella or eucalyptus. Avoid spraying directly onto polished or lacquered surfaces.
Skincare blend0.5–1% in lightweight carrierBest for oily or combination skin. Avoid on sensitive or very dry skin. Patch test 48 h before full application. Do not use undiluted. Max adult dermal 5% (T&Y).

Dầu nền phù hợp

JojobaLightweight non-comedogenic wax ester; ideal for oily and combination skin; long shelf life helps preserve the oxidation-sensitive monoterpene fraction.
Fractionated coconutOdourless, very lightweight liquid; absorbs rapidly; extends shelf life of monoterpene-rich oils; versatile base for massage and body-spray applications.
Sweet almondNeutral scent, mild emollience, widely tolerated; good general-purpose carrier for massage blends targeting normal to combination skin types.
GrapeseedHigh linoleic acid, very lightweight; well-suited to oily skin as a non-greasy base; reinforces skin barrier without adding congestion risk.
RosehipRich in polyunsaturated fatty acids; adds mild anti-inflammatory co-benefit at low inclusion rates (10–20%) within a blended carrier formula.

Kết hợp tốt với

FloralGreenWoodyHerbaceous

Blend kinh điển

[Tisserand & Young] Ch.13 p.545 (Combava leaf)
[Lawrence Essential Oils] p.122 chemistry
[Manosroi et al] chemopreventive IC50 KB + P388 cell lines

An Toàn

Giới hạn da tối đa

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Giới hạn IFRA

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Thai kỳ & Cho con bú

Tam cá nguyệt 1Unknown
Tam cá nguyệt 2Unknown
Tam cá nguyệt 3Unknown

Giới hạn độ tuổi

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Bảo quản

Bảo quản nơi tối, mát

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Hồ Sơ Hoá Học Chi Tiết
§3 Chemical Profile — chemotype, constituent ranges, adulteration

Combava leaf — Lawrence p.122

ConstituentRange
Citronellal58.9–81.5% (dominant — signature marker)
Citronellyl acetate0.9–5.1%
Isopulegol0.3–4.9%
Sabinene1.6–4.8%
Linalool2.9–4.7%
β-Pinene0.2–1.5%
β-Myrcene0.4–1.4%
γ-Terpinene0.1–1.1%

Chemistry insights

  • Citronellal 58.9–81.5% is the signature dominant — this oil is effectively a citronellal-dominant monoterpene-aldehyde oil, functionally similar to [[citronella-java]] (~40% citronellal) and [[citronella-sri-lanka]] (~5–15% citronellal; geraniol/citronellol dominant instead) + shares the aldehyde-rich chassis with [[lemongrass]] (citral) and [[melissa]] (citral). Unusual to find such high citronellal concentration in Rutaceae — most citronellal-rich oils are Poaceae (lemongrass / citronella) or Lamiaceae chemotypes.
  • Chemistry completely INVERTED from [[combava-fruit]] (fruit peel) despite SAME SPECIES:
    • Leaf citronellal 58.9–81.5% vs fruit peel citronellal 0.4–16.8% (20–80× difference)
    • Leaf β-pinene 0.2–1.5% vs fruit peel β-pinene 25.9–31.5% (dominant role swap)
    • Leaf sabinene 1.6–4.8% vs fruit peel sabinene 15.6–20.4%
    • Leaf (+)-limonene absent from Lawrence table vs fruit peel 5.3–13.8% → Two chemically-distinct oils from same plant. Plant-part verification on CoA is critical.
  • Isopulegol 0.3–4.9% is a cyclization artifact/intermediate from citronellal (acid-catalyzed or thermal) — normal minor in citronellal-rich oils, not a red flag.
  • Citronellyl acetate 0.9–5.1% contributes ester-green-fruity character to the signature.
  • Zero furocoumarin pathway: Rutaceae peel oils (bergamot / lemon / lime / grapefruit) concentrate furocoumarins via cold-pressing of peel oil glands; STEAM DISTILLATION of leaves leaves non-volatile furocoumarins in still residue regardless of plant family. Combava leaf is non-phototoxic on this mechanistic basis.
  • Aldehyde oxidation: Citronellal + isopulegol + monoterpene aldehydes are susceptible to oxidation (→ potential sensitization post-oxidation) and polymerization. Store airtight + dark + cool; BHT 0.1% or α-tocopherol as antioxidant. Shelf ~12–18 months.
  • Anticarcinogenic constituent signal: Citronellal displays anticarcinogenic activity per Ch.14 Constituent profiles. Combava leaf oil IC50 1.148 mg/mL KB (human mouth epidermal carcinoma) + 0.398 mg/mL P388 (mouse leukemia) — "moderate" per Manosroi 2005 (the fruit peel was more potent at IC50 99/75 µg/mL — 15× stronger). Research-frontier NOT clinical cancer claim.
Công Dụng Trị Liệu Chi Tiết
§10 Therapeutic Uses — skin, emotional, physical, respiratory
  • Modern aromatherapy: Limited availability but niche therapeutic uses as uplifting / mental-focus / insect-repellent accord (citronellal shared mechanism with [[citronella-java]]). Not a staple.
  • Culinary + cultural: The leaf itself is a Southeast Asian cuisine cornerstone (Thai / Cambodian / Indonesian / Malaysian / Vietnamese). Fresh-leaf exposure is authoritative-safe; EO is a concentrated extract with different exposure class.
  • Insect-repellent: Citronellal is a documented topical mosquito repellent constituent. Combava leaf EO shares this property mechanistically with citronella. Commercial + artisan DIY repellent formulations.
Năng Lượng & Ngũ Hành
§11 Energetics — TCM, Ayurveda, aromatic energetics
  • Five-element: Mộc-Hỏa (Wood–Fire — citrus-green-bright aldehyde ethic + uplifting signature).
  • Traditional Southeast Asian cultural significance: kaffir lime / makrut is a cuisine + ritual / spiritual-cleansing ingredient across Thailand, Cambodia, Indonesia, Malaysia. Traditional use predates EO isolation by centuries.

Dữ Liệu Kỹ Thuật Y Khoa

§14 Renderer Contract — Tisserand & Young V2.2

Thông Số Định Lượng

hazards
[]
phototoxic
false
safety_level
safe
cap_derivation
framework_default
oxidation_risk
medium
drug_interactions
[]
shelf_life_months
15
max_dilution_adult
5
contraindicated_all
false
max_dilution_elderly
5
max_oral_dose_mg_day
700
max_dilution_child_2_6
3
max_dilution_sensitive
3
max_dilution_adult_face
5
max_dilution_child_6_12
5
contraindicated_children
false
contraindicated_pregnancy
false
max_dilution_child_under2
2
max_dilution_pregnancy_1st
5
max_dilution_pregnancy_2nd
5
max_dilution_pregnancy_3rd
5

Tài Liệu Y Khoa Tham Khảo

  • Tisserand & Young (2014) Essential Oil Safety 2nd ed — Ch.13 p.545 (Combava leaf)
  • Lawrence Essential Oils — p.122 chemistry
  • Manosroi et al (2005) — chemopreventive IC50 KB + P388 cell lines