- Chamaemelum nobile (L.) All. — synonym Anthemis nobilis L. (cùng cây, tên cũ); Asteraceae, aerial parts of flowering plant, steam distilled. KHÔNG phải Chamomile German/Blue — khác chi (Chamaemelum vs Matricaria) và khác chemistry class hoàn toàn (esters vs sesquiterpenes/azulenes).
- Hazards: None known. Contraindications: None known (all routes). — T&Y p.522–523, Safety summary. Archetypal low-risk oil cùng nhóm với Lavender True.
- Chemistry dominated by angelate + butyrate esters (Chialva 1982, Srinivas 1986, Zani 1991, Lawrence 1998f): isobutyl angelate 0–37.4% + butyl angelate 0–34.9% + 3-methylpentyl angelate 0–22.7% + isobutyl butyrate 0–20.5% + isoamyl angelate 8.4–17.9%. Wide composition variation batch-to-batch.
- Max dermal: No limit T&Y (SYMELab 5% platform cap per convention). Non-phototoxic (Meneghini 1971 + Opdyke 1974 p.853). LD₅₀ rat oral > 5 g/kg + rabbit dermal > 5 g/kg non-toxic.
- JECFA 2003 "no safety concern" verdict cho isobutyl angelate (food flavoring intake); GRAS. Lành nhất trong nhóm chamomile cho pregnancy + pediatric — framework defaults apply without special caps.
Tổng Quan
- Danh pháp khoa học
- Chamaemelum nobile (L.) All.
- Họ thực vật
- Asteraceae (Compositae)
- Bộ phận dùng
- Flower heads — "double" cultivar flower heads (mostly ray florets); harvested at full bloom June–Aug
- Phương pháp chiết xuất
- Steam distillation; traditional copper or stainless steel stills; short distillation time (1.5–2.5 h
- Màu sắc
- Pale blue to pale blue-green (fresh distillate, trace chamazulene); fades to pale yellow or colourless on storage; water-white to pale golden in older batches; **significantly less blue than German chamomile** (which is intensely navy-blue)
- Phân loại nốt hương
- Nốt Top
- Hương thơm
- Middle note (fading into Base note depth); **the most "complex," "fruity-apple-herbal" and "surprisingly intense" EO in this database relative to its delicate reputation**; opening: fresh apple-fruity, sweet-herbaceous; heart: warm chamomile-herbal, honey-sweet, straw-like; dry-down: warm woody-balsamic; **CRITICAL NOTE: Roman chamomile EO smells very different from Roman chamomile TEA — the tea (chamomile herb infusion) is gentle, floral-sweet; the EO is intensely fruity-herbal-apple-medicinal**; this catches first-time users off-guard; dilution critical for pleasant results
- Chemotype / Cultivar
- Single species — no formally named CT; however, two key commercial types:
Các quốc gia sản xuất chính
Tình trạng tại Việt Nam
⭐★★★☆ — imported; RAREST and MOST EXPENSIVE single-herb EO in this entire database relative to other common oils; 200,000–800,000 VND/5–10ml for authentic Roman chamomile EO (5ml often the most common sold unit due to price); German chamomile often sold as "chamomile" at much lower price — critical to distinguish; significant quality variation; authentic Roman chamomile is one of the most frequently adulterated single-ingredient EOs due to high price; VN specialist aromatherapy importers carry stock; request GC/MS
Fresh apple-fruity, sweet-herbaceous, warm straw-honey, slightly medicinal-chamomile, complex and surprisingly intense; entirely different from German chamomile (which is deeply blue-medicinal-azulenic) and from chamomile tea aroma
Táo tươi ngọt-thảo dược – ấm rơm mật ong – thảo dược cúc La Mã – hơi dược thảo – phức tạp và mạnh hơn bạn nghĩ; KHÁC HOÀN TOÀN với hương cúc La Mã trong trà herbal — EO đậm và sắc hơn nhiều
3–6 hours (esters tend to be more volatile than terpenols); 6–12 hours on fabric; good fixation at base note level from pinocarveol + caryophyllene minor components
Xuất sắc — anti-inflammatory + soothing; high ester content skin-conditioning; 0.5–1% trong calendula macerate or rosehip; warm straw-sweet aroma pleasant in rich face balm
Tốt — antimicrobial (isobutyl angelate vs S. aureus); anti-inflammatory; 0.5–1% trong jojoba; helps reduce inflammation around breakouts; not primarily astringent like geranium but very gentle anti-bacterial + calming
Tốt — anti-inflammatory + antioxidant + skin conditioning; 0.5–1% trong rosehip + marula; not as strongly anti-aging as geranium Bourbon but excellent "calming-anti-inflammatory" dimension for mature sensitive skin
Tốt — calming T-zone redness + oiliness while conditioning dry zones; 0.5–1% trong jojoba; appropriate for most combination skin formulations
Tên gọi tại Việt Nam
Trong Y học cổ truyền VN
KHÔNG có YHCT truyền thống VN với Chamaemelum nobile / Anthemis nobilis - Hoa cúc VN trong YHCT là Chrysanthemum morifolium (cúc trắng/cúc hoa vàng): trị sốt, viêm mắt, hạ huyết áp, giải độc — hoàn toàn khác cúc La Mã về hóa học và tác dụng - Trong cộng đồng aromatherapy VN hiện đại: - Roman chamomile = "tinh dầu VIP cho trẻ em" — không. 1 cho sleep + anxiety của bé - Spa cao cấp HN/HCM (trẻ em): dùng Roman chamomile cho baby massage + bath bomb sản phẩm - DIY formulators VN cao cấp: dùng trong
Mua hàng tại VN
Giá: 200,000–800,000 VND / 5ml (phổ biến nhất là 5ml vì giá); đắt thứ 2–3 trong database (sau rose absolute và nhất là neroli) - Nguồn: Tisserand Aromatherapy (UK) distributors VN; Eden Botanicals USA distributors; Plant Therapy; specialist EU organic importers - CẢNH BÁO QUAN TRỌNG: Roman chamomile là EO bị làm giả + mislabel nhiều nhất trong segment herbal EOs tại VN: 1. German chamomile (rẻ hơn) bán là "Roman chamomile" — detect bằng màu (deep blue = German, pale blue = Roman) VÀ GC/MS (chama
Pha Chế & Hòa Hợp
BEST EVIDENCE IN DATABASE FOR ANXIETY AND SLEEP (aromatherapy inhalation route): PMID 31006899 meta-analysis (12 RCTs) — chamomile significant improvement in GAD (HAM-A scale MD = -1.43 P=0.007 at 2 weeks; MD = -1.79 P=0.0097 at 4 weeks); sleep quality significantly improved (SMD = -0.73, 95% CI [-1.23, -0.23], P<0.005); PMC10763144 2024 RCT — aromatherapy chamomile EO in ACS hospitalized patients: anxiety ↓ (intervention: -5.2±1.9 vs placebo -1±1.18 P<0.001); PMC11109927 2024 systematic review confirms chamomile anxiolytic effect; darwin-nutrition.fr: 56 coronary patients stent placement — chamomile + lavender + neroli blend aromatherapy → anxiety ↓ + sleep quality ↑; isobutyl angelate (25–40%) antispasmodic + ester-class sedative mechanism + possible apigenin HPA axis modulation.
Ref: PMID 31006899; PMC11109927; PMC10763144
PMC12269088 2025 meta-analysis (RCTs) — chamomile significant reduction in pain and mucosal inflammation (statistically significant p<0.05); effective in wound healing + epithelialization (Glowania double-blind 14 patients: chamomile faster wound healing than corticosteroids); chamomile extract more effective than corticosteroids in complete wound healing speed (Martins et al. 2009); chamazulene (trace) + caryophyllene + alpha-pinene + isobutyl angelate anti-inflammatory synergy; PMC10785696 2024 (MCEO — German chamomile but mechanism applicable) PI3K/Akt/mTOR + p38MAPK pathway inhibition.
Ref: PMC12269088; PMC9822300
Isobutyl angelate (25–40%) + entire angelate/tiglate ester complex = powerful antispasmodic; mechanism: esters hydrolyse to aliphatic alcohols + organic acids → smooth muscle Ca²⁺ channel inhibition; IBS, dysmenorrhoea, digestive cramping, muscle tension; supported by PMC9611340 2022 comprehensive review.
Ref: PMC9611340
PMID 31006899 meta-analysis: significant sleep quality improvement; darwin-nutrition.fr: coronary patients — chamomile blend → better sleep quality; ester-dominant profile contributes to parasympathetic activation; traditionally "the premier children's calming EO" (with appropriate dilution).
Ref: PMID 31006899; PMC11109927
Isobutyl angelate active vs S. aureus and Klebsiella pneumoniae; moderate vs C. albicans; Salmonella + E. coli inhibition (darwin-nutrition.fr, 2024); PMC9611340 confirms antimicrobial; weaker than more monoterpene-rich oils (tea tree, oregano).
Ref: PMC9611340; darwin-nutrition.fr 2024
Chamomile extract double-blind: wound healing (5.3 days chamomile vs 6.3 days antibiotic); epithelialization promotion; topical chamomile oil eczema relief (PMC9611340); anti-inflammatory + antimicrobial + tissue-regenerative combination; herbapolonica.pl review confirms skin benefits.
Ref: PMC12269088; PMC9611340; PMC9822300
PMC12269088 meta-analysis: significant pain reduction vs control; caryophyllene CB2 agonist mechanism; myrcene analgesic.
Ref: PMC12269088
Darwin-nutrition.fr: 54 chronic asthmatic patients — chamomile inhalation 100mg/kg 21 days → airway relaxation + improved respiratory function; antispasmodic mechanism on bronchial smooth muscle.
Ref: darwin-nutrition.fr 2024
PMID 31006899 / Wiley PTR 2019 — meta-analysis
12 RCTs chamomile; GAD HAM-A: MD -1.43 (P=0.007) at 2wk, -1.79 (P=0.0097) at 4wk; Sleep quality SMD -0.73 (P<0.005); efficacious + safe
Systematic review + meta-analysis — HIGHPMC11109927 (2024) systematic review
Oral chamomile anxiolytic confirmed; HPA axis + neurotransmitter pathway; safe
Systematic review — HighPMC10763144 (2024 RCT)
Chamomile EO aromatherapy ACS patients: anxiety ↓ (-5.2±1.9 intervention vs -1±1.18 placebo, P<0.001)
Grade B RCT — HighPMC12269088 (2025 meta-analysis)
Chamomile RCTs: significant pain reduction + mucosal inflammation ↓ + wound healing ↑; faster epithelialization vs corticosteroids
Meta-analysis RCTs — HighGlowania 1987 double-blind (n=14)
Chamomile extract: wound healing 5.3 days vs antibiotic 6.3 days; epithelialization ↑
Grade B DB — Moderate (old but landmark)darwin-nutrition.fr (2024)
56 coronary pre-stent patients: chamomile+lavender+neroli blend → anxiety ↓ + sleep ↑; 54 asthmatic patients chamomile inhalation → airway relaxation + respiratory function ↑
Clinical evidence — ModeratePMC9822300 (2022 review)
Chamomile traditional uses + chemical constituents + pharmacological properties; anti-inflammatory, antispasmodic, anxiolytic, antimicrobial confirmed
Comprehensive review — HighPMC9611340 (2022)
Therapeutic applications: anti-inflammatory, wound healing, antimicrobial, antifungal, antioxidant — multi-mechanism confirmed
Comprehensive study — HighCIR Safety 2013
Anthemis nobilis EO no dermal irritation or sensitisation in human repeated insult patch test (HRIPT); safe at normal cosmetic concentrations
Safety study — HighTâm trạng: Deeply Calming + Sedative + Emotionally Soothing + Inner-Child Healing — Roman chamomile is the premier "nervous system reset" oil in this database; distinguished from lavender (which calms AND uplifts): Roman chamomile moves toward deep stillness, release of resistance, surrendering tension; particularly indicated when the nervous system is "stuck" in hyperarousal (anxiety, insomnia, overthinking, somatic tension); the ester-dominant chemistry (55–75% esters) is the most antispasmodic, most sedative chemical class in aromatherapy — and Roman chamomile has THE highest ester % of any widely-used therapeutic EO; "the child's oil" — gentleness of mechanism combined with potency of effect makes it uniquely suited to all ages when properly diluted
Chakra
Solar Plexus ★★★★★ (Manipura
Ngũ hành
Earth
| Phương pháp | Liều lượng | Ghi chú |
|---|---|---|
| Diffusion (khuếch tán) | 1–3 drops / 100ml | REDUCE dose — Roman chamomile is STRONG; 1 drop + 3 drops lavender = anxiety/sleep blend; 30–45 min; children's room: 1 drop max |
| Topical massage (massage) | 0.5–2% dilution | 3–12 drops per 30ml; adults: 2%; children 3–10yr: 0.5–1%; never undiluted; sweet almond or jojoba; PMS abdominal 1.5% + clary sage |
| Bath (tắm) | 3–5 drops in carrier | Pre-dilute in full fat milk or jojoba; 3 drops = adult; 1–2 drops in baby bath (>6 months, diluted); wind-down evening bath |
| Inhalation (hít) | 1 drop tissue / inhaler | Acutely calming; anxiety attack first-aid; 1 drop = sufficient; 5–10 min; lavender + chamomile inhaler = clinical anxiety protocol |
| Skincare | 0.5–1% in face product | 3–6 drops per 30ml; sensitive/reactive skin; eczema relief serum; wound healing cream; 1% maximum leave-on sensitive skin |
| Children / Infant | 0.1–0.5% | 0.1% for <2yr (IFRA guideline; after medical clearance); 0.3–0.5% age 2–10yr; diffusion preferred over topical for infants |
| Compress | 2–3 drops in 500ml warm water | Abdominal compress for IBS cramps; facial compress for skin soothing |
Dầu nền phù hợp
Kết hợp tốt với
Blend kinh điển
An Toàn
Giới hạn da tối đa
2%
Giới hạn IFRA
Roman chamomile oil (Anthemis nobilis flower oil) is not individually IFRA-restricted as of IFRA 51; no specific maximum in perfume bases; standard good practice dilutions apply; component angelate esters not individually restricted
Thai kỳ & Cho con bú
Giới hạn độ tuổi
Xem chi tiết
- x *Dermal limits:**
- x **No phototoxicity** — Roman chamomile EO is NOT phototoxic (unlike many citrus EOs); no bergapten or furocoumarins; safe for daytime topical use
- x *Pregnancy & Breastfeeding (Thai kỳ):**
- x T1: **AVOID** — antispasmodic esters + epidemiological miscarriage concern; uterotonic potential at therapeutic doses
- x T2: **AVOID / Extreme Caution** — same rationale; brief aromatherapy inhalation (1 drop tissue, <10 min) only if medically supervised
- x T3: **Caution** — same; avoid topical abdominal; diffusion (1 drop, brief, ventilated room) may be acceptable in T3 under guidance
- x Breastfeeding: **Caution** — limited data; avoid topical on breast; diffusion probably safe at 1 drop
- x *Age Restrictions:**
- x <3 tháng: AVOID ALL topical; diffusion maximum 1 drop very large ventilated space
- x 3 tháng – 6 tháng: Diffusion only (1 drop); avoid topical
- x 6 tháng – 2 tuổi: Topical maximum 0.1–0.2% (2 drops/30ml carrier); diffusion 1 drop/large room
- x 2–6 tuổi: 0.3–0.5% topical; 1–2 drops diffusion; **Roman chamomile is considered one of safest EOs for children 2+ with proper dilution**
- x 6–12 tuổi: 0.5–1% topical; standard children's dosing
- x 12+: Standard adult with patch test
- x *Drug Interactions:**
- x **CYP450 enzymes:** In vitro chamomile extract inhibition of CYP1A2 and CYP3A4; theoretical drug metabolism interaction at oral doses; aromatherapy topical/inhalation: not clinically significant
- x **Antiepileptics:** Caryophyllene CB2 activity — theoretical; no documented clinical interaction at aromatherapy doses
- x *Contraindications:**
- x Known Compositae/Asteraceae allergy (ragweed, chrysanthemum, feverfew, arnica) — ABSOLUTE for topical; patch test before first use
- x Pregnancy T1 (AVOID) — uterotonic ester concern
- x Known allergy to chamomile herb/tea
- x Pre-surgical sedation protocol (may potentiate CNS depression)
- x *Quality markers (Kiểm tra chất lượng):**
- x **Genuine Roman Chamomile GC/MS authentication:**
- x **Isobutyl angelate ≥25%** ✓ — PRIMARY MARKER
- x **Total esters ≥55%** ✓
- x **Chamazulene ≤1%** ✓ (>5% = German chamomile contamination/mislabelling)
- x 2-Methylbutyl angelate 12–22% ✓
- x Isoamyl isobutyrate 8–16% ✓
- x Isoamyl tiglate 8–20% ✓
- x **COLOUR:** Pale blue → pale yellow = authentic (NOT deep navy blue = German chamomile)
- x **Adulteration risks — VERY HIGH (most expensive common herbal EO):**
- x German chamomile mixed in — detectable by chamazulene >5% and blue-dominant colour; completely different therapeutic profile
- x Other Anthemis/Chamomile species (A. arvensis, A. cotula) — inferior ester profile; lower isobutyl angelate
- x Synthetic ester dilution — isobutyl angelate + isoamyl tiglate commercially available; IRMS detection required; proportional anomalies in minor esters betray adulteration
- x Palmarosa or other cheap EOs added to bulk — GC-MS shows geraniol/citronellol peaks
- x Dilution in odourless mineral oil or fractionated coconut — visual/physical test; GC-MS confirms
Genuine Roman Chamomile GC/MS authentication: - Isobutyl angelate ≥25% ✓ — PRIMARY MARKER - Total esters ≥55% ✓ - Chamazulene ≤1% ✓ (>5% = German chamomile contamination/mislabelling) - 2-Methylbutyl angelate 12–22% ✓ - Isoamyl isobutyrate 8–16% ✓ - Isoamyl tiglate 8–20% ✓ - COLOUR: Pale blue → pale yellow = authentic (NOT deep navy blue = German chamomile) Adulteration risks — VERY HIGH (most expensive common herbal EO): - German chamomile mixed in — detectable by chamazulene >5% and blue-domin
Bảo quản
Thủy tinh hổ phách; <15°C ideal (refrigerate tại VN — REQUIRED for preservation of angelate esters in humid/hot climate); tránh ánh sáng + nhiệt độ cao; ester-dominant EOs hydrolyse faster than alcohol-dominant oils in heat + humidity; shelf life 2–3 năm kín tốt; 12–18 tháng đã mở; VN storage note:
