- Juniperus oxycedrus L. (Cupressaceae) — wood, by destructive distillation (pyrolysis-tar class, same class as [[birch-tar]] — only 2 such oils in B216). Plant = prickly juniper; oil name = cade (synonym: juniper tar). This file covers the rectified (purified) form only; for the crude form see [[cade-unrectified]] (distinct safety class + IFRA regulatory status).
- IFRA permitted with PAH cap. IFRA 2009: rectified cade may be used as fragrance ingredient only if final product (alone or combined with [[birch-tar]]) contains ≤1 ppb total PAHs (benzo[a]pyrene + 1,2-benzanthracene). Rectified benzo[a]pyrene residual up to 20 ppb in the oil itself — "less than the concentration found in some foodstuffs" (Bouhlal 1988a).
- T&Y hazards: Toxicity. Contraindications: "Should not be taken in oral doses." Non-phototoxic (Opdyke 1975 p.733–734); 2% on 25 volunteers non-irritating + non-sensitizing; 3% = 2 mild irritation reactions in 25 volunteers (Bouhlal 1988a). Acute oral LD50 rats 8.0 g/kg (Jenner 1964), ≥5 g/kg (alternate); dermal LD50 rabbits >5 g/kg.
- Chemistry (rectified, Abisset 2004): δ-cadinene 24.2% + torreyol+3 alcohols 9.3% + epicubenol 8.7% + zonarene 8.1% + β-caryophyllene 6.1% + (E)-calamenene 5.1% + α-caryophyllene 4.3% + 14-hydroxy-α-caryophyllene 2.8%. Sesquiterpene-hydrocarbon-dominant post-rectification — PAHs + volatile phenolics largely removed (benzo[a]pyrene residual ~20 ppb vs 8,000 ppb in [[cade-unrectified]]).
- Destructive-distillation pyrolysate rail (CLASS-LEVEL): Wood burns during distillation → PAH formation same mechanism as cigarette smoke + charred food. Not a steam-distilled oil — safety profile fundamentally different from all other juniper oils ([[juniper-berry]], [[juniper-needle]] = J. communis steam distillate; [[cedarwood-virginian]] = J. virginiana heartwood steam distillate). Do NOT extrapolate.
Tổng Quan
- Danh pháp khoa học
- Juniperus oxycedrus L.
- Họ thực vật
- Cupressaceae
- Bộ phận dùng
- Wood
- Phương pháp chiết xuất
- destructive_distillation
- Màu sắc
- —
- Phân loại nốt hương
- Nốt Base
- Hương thơm
- —
- Chemotype / Cultivar
- —
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Smoldering ancient timber, dark leathery smoke, charred resinous ember, dry and primal woodsmoke, muted ancestral darkness
Gỗ cổ thụ âm ỉ than tàn, khói da thuộc sẫm tối, nhựa cháy sém bên than đỏ, khô khan nguyên thủy, tối trầm như hơi thở tổ tiên
2–4 giờ
Tên gọi tại Việt Nam
Pha Chế & Hòa Hợp
Phenolic constituents (guaiacol, cresols) in rectified cade are thought to reduce itch signaling at the cutaneous level, consistent with traditional dermatological use in psoriasis and chronic eczema.
Ref: Tisserand & Young 2014, Ch.13 p.486–487
Guaiacol, cresols, and cadinene fractions contribute antimicrobial activity against skin-surface pathogens, supporting traditional use in infected dermatoses.
Ref: Opdyke, D.L.J. (1975) Food and Cosmetics Toxicology 13, p.733–734
Tar-derived phenols promote controlled desquamation of hyperkeratotic skin layers; rectified cade retains this property while substantially reducing PAH load relative to unrectified grade.
Ref: Tisserand & Young 2014, Ch.13 p.486–487
Cytotoxic phenolic fractions disrupt the cuticle and neuromuscular function of ectoparasites (lice, Sarcoptes scabiei), consistent with centuries of veterinary and human antiparasitic use.
Ref: Tisserand & Young 2014, Ch.13 p.486–487
Sesquiterpene cadinene fractions may modulate local cutaneous inflammation; evidence is preclinical and class-extrapolated rather than demonstrated specifically for rectified cade.
Ref: class-extrapolation from juniper berry (Juniperus communis)
AI-summary
No modern RCT-grade clinical evidence exists for rectified cade EO specifically. Opdyke (1975) conducted acute oral LD50 and dermal irritation testing in animals. Bouhlal et al (1988a) performed volunteer patch testing confirming tolerance only at very low concentrations. Phillips et al (1990) and Schoket et al (1990) documented genotoxicity and DNA adduct formation at the tar class level (PAH-driven), establishing the mechanistic rationale for the strict 0.1% dermal cap even after rectification. Traditional dermatology used unrectified cade for psoriasis and eczema, but those outcomes are not directly transferable to the rectified EO grade. Summary: traditional dermatological use well-documented; no RCT evidence for rectified cade EO.
NarrativeTâm trạng: Grounding, Balancing
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Ngũ hành
thuy
| Phương pháp | Liều lượng | Ghi chú |
|---|---|---|
| Topical spot application | 0.1% in carrier oil (1 drop per 20 ml) | Hard maximum: 0.1% adult dermal cap (T&Y 2014). Affected skin only — psoriasis plaques, eczema. Avoid face and mucous membranes. Never undiluted. Contraindicated in pregnancy and children. |
| Medicated scalp treatment | 0.1% in shampoo base or jojoba (1 drop per 20 ml) | Rinse-off reduces systemic absorption. Leave-on must not exceed 0.1%. For seborrheic dermatitis and scalp psoriasis in adults only. Patch test required before first use. |
| Compress (localized) | 0.1% in warm water with dispersant | Warm compress over affected skin plaques only. Limit application area. Contraindicated in pregnancy; not for children. Wash hands immediately after contact with preparation. |
| Diffusion (atmospheric only) | 1–2 drops maximum in 100 ml water | Smoky, tarry, phenolic aroma. Very low volumes only. Not for direct therapeutic inhalation. Avoid spaces shared with pregnant women or children due to absolute contraindications. |
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