- Aquilaria malaccensis Lam. (Thymelaeaceae). Also: Aquilaria sinensis (Lour.) Gilg. + A. crassna Pierre (unlisted here but a major Vietnamese-Cambodian source) + A. agallocha (now synonym of malaccensis). Source: fungus-infected heartwood only — healthy wood produces no agarwood. Steam distillation + CO₂ extracts. "Agarwood / Oud / Ood / Trầm hương / Kỳ nam / Aloeswood / Eaglewood / Lignum aloe".
- Fungal-infection heritage rail (CRITICAL): Agarwood oil is distilled ONLY from wood that has been infected by Phialophora parasitica or similar fungi. The infection stresses the tree into producing a dark, resinous, fragrant heartwood (agar) as a defense response. Healthy, uninfected Aquilaria produces no agarwood. Historically, natural infection was rare — hence the extreme price. Today, intentional inoculation is the industrial norm.
- Chemistry (Lawrence 1998e, Vietnamese sample): 2-(2-(4-Methoxyphenyl)ethyl) chromone 21.2–33.0% + 2-(2-Phenylethyl) chromone 16.1–23.6% + Oxo-agarospirol 1.4–5.3% + Guaia-1(10),11-dien-15-oic acid <4.7% + 6-Methoxy-2-(2-(4-methoxyphenyl)ethyl) chromone 2.0–3.7% + Guaia-1(10),11-dien-15-al 0.4–3.4% + Selina-3,11-dien-9-ol 0.4–2.8% + Selina-3,11-dien-9-one 0.2–2.1%. Chromone-dominant — a rare chemistry class, virtually unique to Aquilaria.
- Hazards: None known. Contraindications: None known. Acute toxicity: no information found. Carcinogenicity: no information found; no known carcinogens in the oil. Agarwood oil vapors are sedative to mice (Takemoto 2008) — supports traditional meditation + sleep-induction use.
- CITES Appendix II rail (CRITICAL sustainability): Aquilaria malaccensis is CITES Appendix II listed: "species that are not necessarily now threatened with extinction but that may become so unless trade is closely controlled." Legitimate trade requires CITES export permits. Cost: 10-15× jasmine absolute — one of the most expensive aromatic raw materials in the world. Strong economic incentive for adulteration; authentication is non-trivial without GC-MS.
Tổng Quan
- Danh pháp khoa học
- Aquilaria malaccensis Lam.
- Họ thực vật
- Thymelaeaceae
- Bộ phận dùng
- —
- Phương pháp chiết xuất
- steam_distillation
- Màu sắc
- —
- Phân loại nốt hương
- Nốt Base
- Hương thơm
- —
- Chemotype / Cultivar
- —
Tình trạng tại Việt Nam
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Sacred smoldering dark wood, ancient temple incense settling on silk, warm resinous depth with quiet animalic richness, solemn and profoundly heavy
Gỗ linh thiêng âm ỉ cháy, khói nhang cổ đại lắng đọng trên tơ lụa, nhựa thơm ấm sâu thẳm, huyền bí như không gian cổ tự, trầm mặc vững chãi
2–4 giờ
Tên gọi tại Việt Nam
Pha Chế & Hòa Hợp
Agarwood heartwood vapors reduced locomotor activity dose-dependently in mice, indicating CNS-depressant activity attributable to the complex sesquiterpene fraction of the heartwood EO.
Ref: Takemoto (2008) [via B216]
Olfactory pathway activation by agarwood vapor is proposed to modulate limbic-system arousal, supporting emotional calming and meditative states; consistent with Takemoto (2008) sedative data and centuries of cross-cultural meditative use.
Ref: Takemoto (2008) [via B216]; Tisserand & Young 2014, Ch.13 p.434
Topical application of diluted agarwood EO is traditionally used in Ayurvedic and East Asian medicine as a skin tonic; no constituent-level mechanistic data available from provided citations.
Ref: Tisserand & Young 2014, Ch.13 p.434
Sesquiterpene constituents characterising all three geographical chemotypes (Lawrence 1998e; Näf 1995; Bhuiyan 2009) share structural classes with anti-inflammatory sesquiterpenes in related heartwood oils; no direct agarwood-specific mechanistic study in provided citations.
Ref: class-extrapolation from sandalwood and guaiacwood sesquiterpene class; Lawrence (1998e) [via B216]
AI-summary
The sole controlled study in provided citations is Takemoto (2008), a murine sedative-vapor experiment showing dose-dependent locomotor reduction following agarwood inhalation — animal model only, not a human clinical trial. No RCT-grade evidence for any therapeutic action has been located in the citation set. Traditional use across Buddhist, Islamic, Ayurvedic, and Taoist medicine over several centuries provides a strong ethnobotanical signal for grounding, anxiety relief, and skin conditioning, but does not constitute clinical-grade evidence. Significant chemotype heterogeneity between Vietnamese (Lawrence 1998e), Indian (Näf 1995), and Bangladeshi (Bhuiyan 2009) sources complicates generalisable evidence assessment.
NarrativeTâm trạng: Grounding, Balancing
Chakra
root
Ngũ hành
thuy
| Phương pháp | Liều lượng | Ghi chú |
|---|---|---|
| Diffusion | 2-4 drops in 100 ml water | Primary aromatherapy use. Suitable for meditation, evening wind-down (thiền định, thư giãn). Session 30–60 min in well-ventilated space. Pairs well with sandalwood or frankincense. |
| Topical massage | 1-2% in carrier oil (3-6 drops per 10 ml) | Well within the 5% adult max dermal limit. Apply to back, chest, or pulse points. Pair with jojoba or sweet almond. Avoid on broken or sensitised skin. |
| Skincare blend | 0.5-1% in carrier oil | Luxury face/neck tonic for mature or dry skin. Pair with rosehip or argan. Perform patch test before first use given significant chemotype variability between sources. |
| Direct inhalation | 1-2 drops on tissue or ceramic ring | Brief on-demand inhalation for acute grounding; 3-5 slow breaths. Avoid prolonged direct inhalation in confined spaces. Not suitable for children under 6. |
| Aromatic personal blend | 2-5% in jojoba oil | Pulse-point application (wrist, neck). Stays within adult max dermal 5%. Oud note is highly persistent; start at 2% and adjust. Verify sourcing origin before use. |
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